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Paʻa Lapatinib (231277-92-2)

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SKU: 231277-92-2. Māhele:

ʻO ka AASraw me ka hōʻano a me ka hana hana mai ka gram a ka papa kauoha nui o ka paupa Lapatinib (231277-92-2), ma lalo o ke kānāwai CGMP a me ka'ōnaehana mālama maikaʻi.

Product Description

ʻO ka Lapatinib pueo video


ʻO ka lapatinib pau nā Pūʻulu Pūʻulu

Name: ʻO ka lapatinib pau
CAS: 231277-92-2
Nā Kaulike Molecular: C29H26ClFN4O4S
Molecular Weight: 581.05
Wahi Manaʻo: 136-140 ° C
Hōʻoia Kōkua: Pūmole
kala like 'ole: ʻO kaʻeleʻeleʻo Crystallineʻeleʻele a iʻole keʻokeʻo


ʻO ka Raw Lapatinib ka pauka i ka hanana Agentoplastic Agent

Nā inoa

Kahi inoa'ī: Lapatinib powder (ka PA tin ib)
Inoa inoa: Tykerb

Ka hoʻohanaʻiaʻana o ka Lapatinib Ula

ʻO ka Lapatinib ka paukiko he lāʻau lāʻau i hoʻohanaʻia me kekahi lāʻau lapaʻau (capcitabine) e mālama ai i nā poʻe me ka maʻi kanulau āpau i pālahalaha i nā mea'ē aʻe o ke kino e HER2 maikaʻi (nā pūpū e hua i ka nui o ka protein i kapaʻia ka mea loaʻa ka'āpana epidermal growth factor-2) , a ua loaʻa mua i kekahi mau maʻi maʻi maʻi umauma'ē aʻe.

Hoʻohanaʻia ka paupa Lapatinib me keʻano o ka lāʻau i kapaʻia he letrozole no ka hoʻoponoponoʻana i nā wāhine postmenopausal with diamone receptor positive, HER2 maʻi maʻi o ka maʻi maʻamau e hōʻikeʻia ai ka hormonal therapy.

ʻO ka maʻi Lapatinib he lāʻau lāʻau i hoʻohanaʻia e mālama ai i ka maʻi kanesa o ka maʻi. Hoʻohanaʻia ia me nā lāʻau'ē aʻe e mālama ai i kekahiʻano o ka maʻi maʻi āpau i pālahalaha i nā wahi'ē aʻe o ke kino aʻaʻole hoʻi i pane i nā maʻi o nā maʻi'ē aʻe.

ʻO ka Lapatinib ka pauka i kekahi hui lāʻau i kapaʻia he mau mea hoʻopalekana kinase e hana ana ma ke kāohiʻana i ka hana a kekahi pūmua e hōʻike ana i nā pūkunia pūʻai e hoʻonui.

ʻO kēia lāʻau i loaʻa i ka papa pālahalaha a laweʻia i kēlā me kēia lā i ka'ōpū'ōpū.

ʻO nā hopena o nā hopena maʻamau o ka Lapatinib e pau i kaʻulaʻula, nā lima a me nā wāwae, ka diarrhea, ka mumū, a me ka nausea.

He aha keʻano o ka paupa Lapatinib

ʻO ka hana maʻamau maʻamau no ka maʻi o ka'ōpū

-HAU2-POSITIVE METASTATIC BREAST CANCER (e like me ka capecitabine): 1250 mg i hoʻokahi manawa i ka lā ma nā lā 1 a hiki i ka 21 me ka hoʻomau pinepineʻana i ka hana houʻana i nā holokū 21 a hiki i ka uluʻana o ka maʻi a iʻole ka hōʻinoʻoleʻia.

-HONELE RECEPTOR-POSITIVE, HER2-POSITIVE METASTATIC BREAST CANCER (e like me ka letrozole): 1500 mg i ka manawa hoʻokahi i ka lā.

Nā mana'o:
-Ke kōkua i kaʻikepili huahana hana no ka capecitabine a me ka'ōlelo lepezōzole.
-HAU2-kūpono i nā maʻi kanesa maʻi e loaʻa i ka maʻi ma ka trastuzumab ma mua o ka hoʻomakaʻana o ka lāʻau lapaʻau me kēia lāʻau lapaʻau me ka capecitabine.

Hoʻohana hoʻohana:
-I hui pūʻia me ka capecitabine no ka hoʻomaʻamaʻaʻana i nā maʻi me ka maʻiʻana o ka umauma āpau a iʻole ka pahūʻau nui o ka HER2 a ua loaʻa iā lākou i mua o ka hoʻolālā me kahi anthracycline, kahiʻauhau, a me trastuzumab.
-I hui pūʻia me ka letrozole no ka mālamaʻana i nā wāhine postmenopausal e loaʻa ana i ka maʻi o ka maʻi me ka hormone receptor-positive diagnon cancer e hoʻomaʻemaʻe i ka HER2 receptor kahi e hōʻikeʻia ai ka hormonal therapy.

Hana Houʻo Renal
Kaʻikepiliʻole e pili ana i nā hoʻololi o nā kinikini; akā,ʻaʻole hiki ke hoʻopiliʻia nā pharmacokinetics o kēia lāʻau lapaʻau ma muli o ka hoʻohaʻahaʻaʻiaʻana o ka mea i emiʻole ma mua o 2% o kahi dose i mālamaʻia e nā puʻupaʻa.

Nā Hoʻoponopono Hou Hana
KA MANAʻO MANAʻO MANAʻO HEPATIC IMPAIRMENT (KA HUI HANA A / B): Kaʻikepiliʻole i loaʻa.

KA HĀ'ĀWAI MANAʻO HEPATIC (KA HUI HĀLĀWAI C): Hoʻoemi i ka pāʻani:
-HER2-ʻO ka maʻi kōkiko kūmā o ka Māniki (me ke kāpili me ka capecitabine): 750 mg / lā.
-Hormone Receptor-Positive, HER2-Hoʻopaʻi i ka Makanua o ka Umi Makike (me ka letrozole): 1000 mg / lā

KA SEPEHE HEPATOTOXICITY OCCURS MA KE KŪLĀ: Hoʻopau loaʻia ke kāpena.

Nā manaʻo: E kauʻia nā manaʻo hoʻohui kūpono ma nā noihana pharmacokinetic; ʻAʻoheʻikeʻikepili i loaʻa.

Hana Hou
KA HOʻOLOʻI I KA MAKAHI I NĀ KULA CYP450 3A4 INHIBITORS a / OR KEKAHI CYP450 3A4 HAWAIʻI: E hōʻalo i ka hana kūpono inā hiki. Kauʻia nā'ōlelo hoʻohui hoʻoholo kūpono ma luna o ka noiʻike pharmacokinetic; ʻAʻole loaʻa nāʻikepili pūnaewele.
KA HOʻOLOʻI I KA MAKAHI CYP450 3A4 INHIBITOR: Hoʻohaʻahaʻa i ka hua i ka 500 mg / lā; eʻae i ka manawa kūpono o ka manawa o ka 1 ma mua o ka hoʻolālā houʻana o kēia lāʻau lapaʻau i ka maʻi i hoʻohana mauʻia inā pauʻole ka mea hoʻopuka.
NĀ KUMU E hoʻohana i ka CYP450 3A4 INDUCER: Ke kauʻana ma luna o ka hopena ma muli o ke kūʻana; e hoʻemi i ka hōʻailona i ka noʻonoʻo i hoʻohanaʻia inā pau ka hoʻopauʻana.
-HER2-ʻO ka maʻi kōkiko kūpona me ke kāpena (me ka capecitabine): Hoʻonuiʻia ka nui a hiki i ka 4500 mg / lā.
-Hormone Receptor-Positive, HER2-Hoʻopaʻi pololei i ka maʻi maʻi āpau (me ka letrozole): Hoʻonui i ka piʻiʻana i ka 5500 mg / lā.

NĀ HOʻOLIMI 2 a iʻole ka mea nui i hoʻolālāʻia e ka LĀKĀ EJECTION (LVEF) A iʻole LVEF KA MAKAHI I KA LĀKAHI I NĀ KULA NĀKAHI: Nānā maikaʻi; hiki ke hoʻouka hou ma ka hoʻemi liʻiliʻi ma hope o ka liʻiliʻi loa o nā 2 wiki inā LVEF hoihoi i ka maʻamau a hoʻomanawanui he asymptomatic.
Ho'ēmi Hoʻolaha:
-HER2-Hoʻopaʻa i ka umauma kōkiko (ma ka hui pū me ka capecitabine): 1000 mg / lā
-Hormone Receptor-Positive, HER2-Hoʻopaʻi i ka Makanua o ka Umi Makike (me ka letrozole): 1250 mg / lā

3 OR NĀ KOINA 1 a iʻole 2 DIARRHEA me ka hōʻailonaʻana i nā mea (kūpono i ka lahilahi o ka ākea o ka'ōpū, 2 ka nui aiʻole ka nui o ka hoʻohuoiʻana a iʻole ka luaʻiʻana, hoʻemi iki i ke kūlana o ka hana, ke kuni, ka liʻiliʻi, neutropenia, Kūkulu i ka 1 Papa a iʻole ka liʻiliʻi.
Ho'ēmi Hoʻolaha:
-HER2-Hoʻopaʻi kūpono i nā maʻi maʻi o ka umauma (e like me ka capecitabine): 1000 mg / lā
-Hormone Receptor-Positive, HER2-Hoʻopaʻi kūpono i ka maʻi o ka'ōpū maʻi: 1250mg / lā
NĀ HĀLĀ 4 DIARRHEA: Hoʻopau loaʻia ke kāpena.

NĀ NUI NUI, 2 HĀMĀLE, a MELELO paha: E manaʻo paha i ka hoʻopauʻana a iʻole ka paʻiʻana o ka hanaʻana; hiki ke hoʻomanaʻo hou i ka manawa i hoʻohanaʻia i ka wā e hoʻopau ai ka meaʻino i ka 1 X a iʻole ka liʻiliʻi.
KA HOʻOPIʻI MAKAHIKI: Hoʻoemi i ka pāʻani:
-HER2-Hoʻopaʻa i ka umauma kōkiko (ma ka hui pū me ka capecitabine): 1000 mg / lā
-Hormone Receptor-Positive, HER2-Hoʻopaʻi kūpono i ka maʻi o ka'ōpū maʻi: 1250mg / lā

Pehea ka hanaʻana o ka momona Lapatinib

Hoʻopiliʻia ka lapatinib pau me ka capecitabine (Xeloda) e mālama i kekahiʻano o ke kanulau maʻi āpau i nā poʻe i hana muaʻia me kekahi mau lāʻau chemotherapy. ʻO ka Lapatinib ka pauka i loko o ka papa o nā lāʻau i kapaʻia he'alepaʻi kinase. Hana ia ma ke kāohiʻana i ka hana o ka pōmaikaʻi kūpilikiʻi e hōʻike ana i nā puʻupuʻa maʻi e hoʻonui. Hiki ke kōkua i ka hoʻomaha aiʻole ka palaka i ka hoʻolahaʻana o nā pūnaeho maʻi.

'Ōlelo Aʻo

E haʻi i nā mea hoʻolaha olakino e mālamaʻoe i ka paupa Lapatinib. Loaʻa kēia i kāu mau kauka, kahu hānai, kauka lāʻau, a me nā niho.
Ināʻoe i ka'ōpū huhū, hāpaiʻana i ka'ōpū, ka wela, aʻaʻole hoʻi e pōloli, kamaʻilio pū me kāu kauka. Hiki paha he mauʻaoʻao e iho ai i kēia mauʻaoʻaoʻaoʻao.
Ua hanaʻia nā'ōpala (ka wela) me ka paukū Lapatinib. I kekahi manawa, ua nui loa ka maʻi diahū a ua make nā make. E kūkākūkā me kāu kauka.
Inā loaʻa iāʻoe nā'ōwili (diarrhea), e kamaʻilio me kāu kauka. Mai ho'āʻo e hana i ka maʻi pīpā me ka nānā muaʻoleʻana me kāu kauka.
E hoʻopaʻaʻia ke koko e like me ka haʻiʻia e ke kauka. E kūkākūkā me ke kauka.
Ponoʻoe e loaʻa nā ho'āʻo o ka naʻau ma ka laweʻana i ka paupa Lapatinib. E kūkākūkā me ke kauka.
E mālama i kaʻaila a me ka waiʻona.
Ināʻoe e noi ana i ka digoxin, e kamaʻilio me kāu kauka. Pono pahaʻoe e hoʻokaʻomaʻo i kāu hana koko ma muli o ke kiʻiʻana me ka paupa Lapatinib.
Hiki paha i kēia lāʻau ke hōʻeha i ka pēpē i hānauʻia ināʻoe e lawe iā ia i kou wā e hāpai ana.
E hoʻohana i ka mana hānau e hiki iāʻoe ke hilinaʻi e pale i ke kōpū i ka laweʻana i ka paupa Lapatinib.
Ināʻoe i hāpai a hāpai pahaʻoe i ka laweʻana i ka paupa Lapatinib, e kāhea i kāu kauka ke kūlike.

Lapatinib Māmā Pā

ʻOiwi kauohaʻo 10grams.
Hiki ke hoʻouna i ka nīnau no ka mea maʻamau (Ma waena o 1kg) i nā hola 12 ma hope o ka uku.
No ke kauoha nui aku hiki ke hoʻokuʻuʻia i ka 3 mau lā hana ma hope o ka uku.

Lapatinib paukū Marketing

E hoʻolakoʻia i ka wā e hiki mai ana.

ʻO ka lapalapa Lapatinib āpau e loaʻa ai nāʻaoʻaoʻaoʻao

A me nā hopena e pono ai, hiki i ka paupa Lapatinib ke loaʻa i kekahi mau mea i makemakeʻoleʻia. ʻOiaiʻaʻole paha e hiki ke hoʻopiliʻia kēia mau hopena a pau, inā hana lākou e pono ai lākou i ke olakino.

E hoʻopaʻa pono me kāu kauka inā loaʻa kekahi o nā hopena ma hope nei i ka laweʻana i ka paupa Lapatinib:

Nā mea maʻamau
Ke hoʻomaha iki a hoʻoluhi paha
ʻehaʻeha
ka wikiwiki a iʻole ke kolohe
ka wela nui
ka paʻa i ka pahu
ka maʻileʻa a me ka nawaliwali
eieao?

ʻO ka'ōpū a me kaʻeha o ka'ōpū a me ke aloha
nā pālaʻuʻula
ʻeleʻele pouli
ua hoʻemiʻia ka makemake
wela
headache
pauʻole kaʻiliʻana o kaʻili
ka nele o kaʻai
nausea a me ka luaʻi
ke kīpē o nā wāwae a me nā wāwae lalo
nā makaʻeleʻele a iʻole kaʻili
ʻAʻohe iʻikeʻia
ʻO ka pīpī, ka peʻe, ka weheʻana i kaʻili
pākī
nā'ōpū
cough
diarrhea
ka pilikia me ka ale
pōniuniu
ka manaʻo nui o ka pilikia a me ka maʻi
hives
ka huʻiʻokoʻa a iʻole ke kaumaha
ka puʻupuʻu a me ka hoʻouluʻana o nā'ōpū ma kahi o nā maka, maka, nā lehelehe, a me nā'ōlelo
nāʻeleʻeleʻiliʻulaʻula, pinepine me ka ulu lāʻauʻulaʻula
ʻeleʻele, mau maka huhū
eha ka' ā'ī
nā maʻi, nā maʻiʻeleʻele, a me nā mea keʻokeʻo ma ka waha a ma nā lehelehe paha
ka māmā o ka hilahila hilahila
Hiki ke loaʻa kekahi mau hopena o ka maʻi Lapatinib i ka mea maʻamauʻole e pono ai ke ola kino. Hiki ke hele aku kēia mau hopena ma ka lawelaweʻana e like me ka hoʻoponoponoʻana o kou kino i ka lāʻau lapaʻau. Eia kekahi, hiki i kāu kauka ola mālama ola ke hiki iāʻoe ke haʻi iāʻoe i nāʻano e pale ai a e ho'ēmi ai i kekahi o kēia mau hopena. E hoʻopaʻa me kāu poʻe kauka ola olakino inā e hoʻomau a pilikia paha kekahi o nā hopena o hope nei a inā he mau nīnau paha kāu e pili ana iā lākou:

ʻO ka mea maʻamau
ʻO ka'ōpū a me ka'ōpū'ōpū
hoʻi i kaʻeha
kāleka
nā lehelehe i hoʻopiʻiʻia
ka welo (ʻoluʻolu)
maloo ili
kapunika
ka momona
eha i loko o nā lima a me nā wāwae
kaʻulaʻula, kīhāhā, aiʻole kaʻiliʻeha
kaʻiliʻana o kaʻili ma nā lima a me nā wāwae
nā maʻi, nā maʻiʻeleʻele, a me nā mea keʻokeʻo ma nā lehelehe, ka'ōlelo, a ma loko paha o ka waha
ka hōʻoluʻolu o ka naʻau, ka huhū, a me kaʻeha
kīhāhā a iʻole ka mumū o ka waha
ke kaniʻana o nā lima a me nā wāwae
hiamoe


Pehea e kūʻai ai i ka momona Lapatinib mai AASraw

1.E hōʻike mai iā mākou ma o mākou leka uila pūnaewele noiʻi, aiʻole skype pūnaeweleka hoʻonohonoho hoʻonohonoho kanaka (CSR).
2.Ke hāʻawi mai i kāu helu a me kāu helu wahi.
3.OUR CSR e hāʻawi iāʻoe i ka helu, ka manawa uku, helu helu, nā puka puka a me ka lā i hōʻea muaʻia (ETA).
4.E ukuʻia a hoʻokuʻuʻia nā waiwai i nā hola 12 (No ke kauoha ma loko o 10kg).
Ua loaʻaʻo 5.Goods a hāʻawi i nā manaʻo.


=

COA

COA 231277-92-2 ka Lapatinib ākea AASRAW

HNMR

ʻO kā mākou Hoʻopiʻi Lapatinib, Lapaʻau Lapatinib e kūʻai aku, Lapa Makani Lapatinib (231277-92-2) hplc≥98% | Nā R & D Hoʻokiʻekiʻe AASraw

ideas

Lapatinib Pākī Lā Lapu:

No ka nīnauʻana i ko mākou mea hōʻailona kōkua (CSR) no nā kiko'ī, no kāu'ōlelo.

Nāʻike & nā hua'ōlelo huahana

Tykerb (231277-92-2) -ʻO ka pepehiʻana i ke kīʻaha umauma