ʻO ka wikiō Lorcaserin (1431697-94-7)

 

 

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Palena Lorcaserin (1431697-94-7) HCL ka paukū mau mea maʻamau

 

Name:	ʻO Lorcaserin ka lepo
CAS:	1431697-94-7
Kaulike Molecular:	C11H15Cl2N
Kaumaha Molecular:	232.1525
Wahi Manaʻo:	212 ° C
Hōʻoia Kōkua:	-20 ℃
kala like 'ole:	ʻO ka pauma

 

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He ahaʻo Lorcaserin

 

Lorcaserin (CAS 1431697-94-7), ke kūʻai ma lalo o ka inoa inoa inoa BELVIQ,ʻo ka mea kumu nuiʻo Lorcaserin HCL ka paukū 846589-98-8. Uaʻaeʻia ka FDA e ka loiloi HCL no nā kānaka obese (me ka helu kuʻuna kino, a BMI paha,ʻo 30 aʻoi aku paha) a iʻole he kaumahaʻole (me kahi BMI o 27 a iʻole paha) a he mauʻano olakino hoʻokahi paha kekahi. e like me keʻano o ka maʻi maʻamauʻo 2, ka nui o ke kaheʻie a me ka cholesterol kiʻekiʻe.

 

He aha kā Lorcaserin e hoʻohana ai

 

ʻO ka māmāʻo XCNUMX-846589-98,ʻo ia ka mea i kapaʻia he "agonists receptor" serotonin. Hoʻohanaʻiaʻo Lorcaserin HCL me kaʻai a me ke bodybuilding e mālama i ka momona, no ka lilo o nā momona. I kekahi manawa ua hāʻawiʻia i ka mālamaʻana i ka mea nui e pili ana me ka cholesterol kiʻekiʻe, ke koko kiʻekiʻe, a me ka diabetes type8. Akāʻo Lorcaserin hydrochloride (Lorcaserin HCL)ʻaʻole ia e mālama i kekahi maʻi olakino (e like me ka maʻi o ka maʻi, ka maʻi nui, ke koko kiʻekiʻe).

 

ʻO ka hoʻokele mechanics o Mozart

 

Lorcaserin hydrochloride lepo e hana ana ma o ka hoʻonāʻana i ka manaʻo - ma ka hoʻonāʻana i nā nānā i ka lolo no ka serotonin, kahi neurotransmitter e hoʻopiʻi ai i nā manaʻo o ka māʻona a me kaʻoluʻolu. ʻO ka mālamaʻana i kaʻai e mālamaʻia e kahi keʻena hānai, kahi i loko o ka pūpū ventromedial o hypothalamus a me ka haleʻai make ma ka piko hypothalamus. Ke kuhi nei nāʻokoʻa mai nā kikowaena kiʻekiʻe a me nā puke āpau e pili ana i ka piko nucleus, kahi e noho aiʻeluaʻano neurons e mālama ana i kaʻai. ʻO ka mea mua, nā pūʻulu hoʻonāʻauʻai e hana ana i ka protein a me ke neuropeptide Y. aʻo ka lua,ʻo ka'āpana hana hoʻopunipuniʻai i loko o ka cocaine a me ka amphetamine (transca) (CART) a me pro-opiomelanocortin (POMC) neurons. POMC loaʻa nā hōʻailonaʻo 5-HT 2C, i ka wā e hoʻopiliʻia ai ka hormone-alpha-melanocyte (alfa-MSH). hana i ka hana he mau mea koho 4-HT 4C maʻamau i nā neurons POMC, aʻo ia ke kumu o ka weheʻana i ka alfa MSH. Hoʻopiʻi houʻia ka MSH ma ka MC5R i loko o ka nucleus ma waho o ka hypothalamus, e hōʻemi ai i ka makemake. Ma nā hana supratherapeutic, lorcaserin kekahi hana ma nā mea loaʻaʻo 2-HT 4B a me nā mea loaʻaʻo 5-HT 2A.

 

Pehea e hoʻohana ai i ka pauka Lorcaserin HCL (CAS 1431697-94-7)

 

He keʻokeʻo ʻo Lorcaserin HCL pauka keʻokeʻo keʻokeʻo keʻokeʻo me ka solubility i ka wai i ʻoi aku ma mua o 400 mg / mL. Loaʻa i kēlā me kēia papa BELVIQ XR 20.8 mg o ka lorcaserin hydrochloride hemihydrate crystalline, like ia me 20.0 mg lorcaserin hydrochloride pauka, a me nā mea hana ʻole e hana nei: microcrystalline cellulose NF; mannitol USP; hypromellose 2208 USP; hoʻopuehu ethylcellulose ʻAno B NF; hypromellose 2910 USP; colloidal silikone dioxide NF; waiʻona polyvinyl USP; polyethylene glycol NF; titanium dioxide USP; talc USP; FD&C melemele # 6 / napoo ka lā FCF; loko alumini; hao hao hao melemele NF; hao hao ʻulaʻula NF; a me ka magnesium stearate NF.

Hiki i ka māmāʻo 846589-98-8 ka'āpana o ka paukū XCUMUM-1 i ka papa pālahalaha a laweʻiaʻo ia i ka manawa maʻamauʻo 2-XNUMX manawa i ka lā, me kaʻaiʻole. Pono e hoʻohanaʻiaʻo Lorcaserin me kahi meaʻai aku i hoʻemiʻia a me ka hoʻolālā hana.

 

Nā kūkākūkā o Lorcaserin

 

-monoamine oxidase inhibitors e like me isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), selegiline (Emsama,'Eldepryl, Zelapar), lagiline (Azilect)

-helectic sequotin receptake (inhibitors) (SSS) like escitalopram (Lexapro), sertraline (Zoloft), citalopram, Palxetine (Paxil), fluoxetine (Prozac, Sarafem), a fluvoxamine (Luvox)

-tricyclic antidepressants e like me trimipramine (Surmontil), amitriptyline (Elavil), nortriptyline (Pamelor, Aventyl), protriptyline (Vivactil), a me clomipramine (Anafranil), a me clomipramine (Anafranil)

 

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Pehea e kūʻai ai i ka momona Lorcaserin HCL (CAS 1431697-94-7) mai AASraw

 

1.E hōʻike mai iā mākou ma o mākou leka uila ʻōnaehana nīnau, a i ʻole skype pūnaeweleka hoʻonohonoho hoʻonohonoho kanaka (CSR).
2.Ke hāʻawi mai i kāu helu a me kāu helu wahi.
3.OUR CSR e hāʻawi iāʻoe i ka helu, ka manawa uku, helu helu, nā puka puka a me ka lā i hōʻea muaʻia (ETA).
4.E ukuʻia a hoʻokuʻuʻia nā waiwai i nā hola 12 (No ke kauoha ma loko o 10kg).
Ua loaʻaʻo 5.Goods a hāʻawi i nā manaʻo.

 

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