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Spermidine trihydrochloride

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ʻO Spermidine trihydrochloride pauka kahi polyamine kūlohelohe i hana ʻia mai putrescine a decarboxylated S-adenosylmethionine (dcSAM) na spermidine synthase, kahi mea hou autophagy inducer a hoʻololi maikaʻi ʻole i ka N-methyl-d-aspartate (NMDA). Ua hoʻohana ʻia ʻo Spermidine trihydrochloride i loko o ʻehā mau ʻano o ka spectroscopy infrared spectroscopy (FTIR) a me nā ana zeta hiki ke loaʻa. ʻIke ākea ʻo Spermidine hydrochloride i ke kūlohelohe a pono no ka ulu ʻana o ka iʻa; Hoʻohana ʻia ma ke ʻano he mea hana i ka noiʻi biochemical; "ʻO ka Spermidine hydrochloride kahi hui polyamine, C7H22Cl3N3, i loaʻa i nā ribosome a me nā meaola ola a me nā hana metabolic like ʻole i loko o nā meaola.

Product Description

Product Name Spermidine trihydrochloride
Kāleka CAS 334-50-9
Ka Lā Molecular C7H22Cl3N3
Kaumaha Kaumaha 254.6
'O Synonyms N- (3-Aminopropyl) -1,4-butanediamine trihydrochloride; 1,8-Diamino-4-azaoctane trihydrochloride; 1,5,10-Triazadecane trihydrochloride; S permidine.3HCl
Keʻano Pauka keʻokeʻo
Ka mālama a me ka lima lima Maloʻo, ʻeleʻele a 0 - 4 C no ka wā pōkole, a i ʻole -20 C no ka wā lōʻihi.

 

Reference

[1] Kishi et al (1998) ʻO Spermidine, kahi agonist pūnaewele polyamine, hoʻonāukiuki i nā hemahema hana hoʻomanaʻo i hana ʻia e ka ālai ʻia o nā receptor muscarinic hippocampal a me mGluRs i nā ʻiole. ʻO Brain Res. 793 311 PMID: 9630697.

[2] Munir et al (1993) Hoʻololi nā Polyamines i nā hopena neurotoxic o NMDA i vivo. ʻO Brain Res. 616 163 PMID: 8358608.

[3] Williams et al (1989) Nā hopena o nā polyamines i ka hoʻopaʻa ʻana o [3H] -MK801 i ka mea loaʻa i ka N-MthD.-aspartate: hōʻike hōʻike lāʻau no ka loaʻa ʻana o kahi pūnaewele ʻike polyamine. Mol.Pharmacol. 36 375 PMID: 2554112.

[4] Galluzzi et al (2017) Hoʻololi i nā lāʻau lapaʻau o autophagy: hiki i nā mea hoʻōla a me nā mea e kū mau ana. Nat.Rev.Drug.Discov. PMID: 28529316.

 

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