Product Description
Anastrozole Powder Video-AASraw
Nā Kiʻi Kumu
| Name: | Anastrozole pauka |
| CAS: | 120511-73-1 |
| Kaulike Molecular: | C17H19N5 |
| Kaumaha Molecular: | 293.37 |
| Wahi Manaʻo: | 81-82 ° C |
| Hōʻoia Kōkua: | RT |
| kala like 'ole: | ʻO kaʻeleʻele'alaʻula |
He aha ka pauka Anastrozole?
ʻO Anastrozole, i kapa ʻia ʻo Arimidex, he lāʻau lapaʻau i loaʻa i ka mea hana anastrozole. Hoʻohana ʻia ia e mālama i ka maʻi kanesa o ka umauma i nā wahine i hala mua i ka menopause. Aia ʻo Arimidex i kahi hui o nā lāʻau i kapa ʻia ʻo 'aromatase inhibitors' e hōʻemi ana i ka nui o ka hormone ʻO ka estrogen i hana ʻia i loko o ke kino ma ke kāohi ʻana i ka hana o kahi enzyme i loko o ke kino i kapa ʻia ʻo 'aromatase. ʻO ka hoʻemi ʻana i ka hana ʻana o ka estrogen he ala ia e kāohi ai i ka ulu ʻana o ka maʻi maʻi umauma no ka mea ua hoʻoulu ʻia ka ulu ʻana o ka umauma e ka estrogen.
He aha ka hana a Arimidex i ke kino?
ʻO Estrogen kahi ʻO ka hormone e hana nui i ka ulu a me ka ulu ʻana o ka maʻi kanesa o ka umauma. Hana ʻia ia i loko o ke kino e kahi enzyme i kapa ʻia ʻo aromatase, nāna e hoʻohuli i nā androgens (nā hormones) i loko o ka estrogen. Ma ka pale ʻana i ka hana o ka aromatase, hoʻemi ʻo Arimidex i ka nui o ka estrogen i loko o ke kino, hiki ke hoʻolōʻihi a hoʻōki paha i ka ulu ʻana o nā maʻi maʻi maʻi umauma.
Ma waho aʻe o kona hoʻohana ʻana i ka mālama ʻana i ka maʻi maʻi umauma, ua hoʻohana ʻia ʻo Arimidex i waho-label e mālama i ka infertility i nā wahine me nā maʻi ovulatory. I kēia mau hihia, hiki iā Arimidex ke kōkua i ka hoʻoulu ʻana i ka ovulation ma ka hoʻohaʻahaʻa ʻana i nā pae o ka estrogen i loko o ke kino, hiki ke hoʻopilikia i ke kaulike hormonal maʻamau e pono ai no ka ovulation.
Hiki i ka hoʻohana ʻana iā Arimidex ke loaʻa i nā hopena he nui i ke kino, ʻo kekahi o ia mau mea e pono ai a ʻo kekahi o ia mau mea hiki ke pōʻino. ʻO kekahi o nā hopena kaulana loa o Arimidex penei:
Hoʻemi ʻia ka pilikia o ka hoʻi hou ʻana o ka maʻi maʻi umauma: Ua hōʻike ʻia ʻo Arimidex i ka maikaʻi i ka hōʻemi ʻana i ka hopena o ka hoʻi hou ʻana o ka maʻi maʻi umauma i nā wahine postmenopausal me ka maʻi maʻi umauma hormone receptor-positive. I loko o nā hoʻokolohua lapaʻau, ua hōʻike ʻia ʻo Arimidex e ʻoi aku ka maikaʻi ma mua o ka tamoxifen, kahi umauma hoʻohana maʻamau lāʻau ʻaʻai, i ka hoemi ana i ka pilikia o ka hana hou.
Pau ka poho: Kekahi o ka hiki aoao waiwai ʻO Arimidex ka nalo iwi, hiki ke hoʻonui i ka pilikia o ka osteoporosis a me ka haʻihaʻi iwi. Estrogen he kuleana koʻikoʻi i ka mālama ʻana i ka nui o ka iwi, a ma ka hōʻemi ʻana i nā pae estrogen, hiki iā Arimidex ke hoʻolalelale i ka nalo iwi. No ka hōʻemi ʻana i ka pōʻino o ka nalo iwi, hiki ke ʻōlelo ʻia nā wahine e lawe ana iā Arimidex e lawe i nā mea hoʻohui calcium a me ka vitamin D, a me ka hoʻoikaika ʻana i ke kaumaha.
Hoʻopihaʻia ke kukū: Hiki iā Arimidex ke hoʻoulu i ka wela a me nā hōʻailona menopausal ʻē aʻe, e like me ka maloʻo ʻana o ka waha a me nā loli o ke ʻano. Hoʻokumu ʻia kēia mau hōʻailona ma muli o ka emi ʻana o nā pae estrogen a hiki ke mālama ʻia me nā loli o ka nohona, e like me ke kāhiko ʻana i nā papa a me ka pale ʻana i nā mea hoʻoulu e like me ka caffeine a me ka waiʻona. nā lāʻau lapaʻau e like me nā antidepressants a me nā lāʻau lapaʻau hoʻololi.
Nā hopena maʻi cardiovascular: He hopena maikaʻi paha ʻo Arimidex i ke olakino cardiovascular ma o ka hoʻemi ʻana i ka pilikia o ka maʻi puʻuwai a me ka hahau ʻana. He hopena pale ka Estrogen i ka ʻōnaehana cardiovascular, a ma ka hoʻemi ʻana i nā pae estrogen, hiki i ka Arimidex ke hoʻonui i ka pilikia o kēia mau kūlana. Eia nō naʻe, ua hōʻike ʻia nā haʻawina e loaʻa paha i ka Arimidex kahi hopena kūʻokoʻa a maikaʻi paha i ke olakino cardiovascular, ʻoi loa i nā wahine i pilikia nui no kēia mau kūlana.
ami eha: Hiki i ka Arimidex ke hoʻoulu i ka ʻeha a me ka ʻoʻoleʻa o nā hui, ʻoi loa ma nā lima a me nā pulima. ʻO kēia hopena ʻaoʻao ua manaʻo ʻia ma muli o ka emi ʻana o nā pae estrogen, hiki ke hoʻopili i ka hana ʻana o ka collagen i nā hui. No ka mālama ʻana i ka ʻeha hui, hiki ke ʻōlelo ʻia nā wahine e lawe ana iā Arimidex e hana i nā hoʻomaʻamaʻa haʻahaʻa, e like me ka yoga a i ʻole ka ʻauʻau, a hiki ke kauoha ʻia i nā lāʻau ʻeha a i ʻole nā lāʻau anti-inflammatory.
I ka hopena, ʻo Arimidex kahi lāʻau lapaʻau i hoʻohana mua ʻia e mālama i ka maʻi kanesa o ka umauma i nā wahine postmenopausal. Hana ia ma ka pale ʻana i ka hana ʻana o ka estrogen i loko o ke kino, hiki ke hoʻolōʻihi a hoʻōki paha i ka ulu ʻana o nā maʻi maʻi maʻi umauma.
ʻO nā hopena maʻamau o ka pauka Arimidex
Arimidex hiki i ka pauda ke hana i nā ʻano hopena ʻino, ʻoi aʻe kekahi ma mua o nā mea ʻē aʻe. He pōkole paha kēia mau hopena ʻino, mau lā wale nō a hiki i kekahi mau pule. Eia naʻe, inā hoʻomau nā hopena ʻino, hopohopo iā ʻoe, a lilo paha i koʻikoʻi, e nīnau i kāu kauka a lāʻau lapaʻau paha.
He mau lima wale nō kēia o nā mea ʻino loa nā hopena i hōʻike ʻia e ka pauka Arimidex mea hoʻohana i nā hoʻokolohua lapaʻau. Hiki ke ʻokoʻa kēia mau hopena ma muli o ka maʻi e mālama ʻia ana e ka lāʻau.
ʻO ka mea maʻamau aoao waiwai i nā poʻe e lawe ana iā Arimidex no ka maʻi maʻi maʻi maʻi mua:
● nā uila wela
● nāwaliwali
● ʻāʻī
● ʻeha nui
● ʻeha hui
ʻO ka mea maʻamau aoao waiwai i loko o ka poʻe e lawe ana iā Arimidex no ka maʻi maʻi umauma maʻi kūloko a i ʻole metastatic:
● nā uila wela
● nausea
● nāwaliwali
● ʻeha nui
● ʻeha poʻo
ʻO ka ʻai ʻana o Arimidex
ʻO ka nui o Arimidex he 1 mg papa i lawe ʻia i hoʻokahi lā. No nā poʻe maʻi me ka maʻi kanesa o ka umauma, pono e hoʻomau ʻia ʻo Arimidex a hiki i ka piʻi ʻana o ka maʻi maʻi. Hiki ke lawe ʻia ʻo Arimidex me ka ʻai ʻole.
No ka mālama ʻana i ka maʻi maʻi umauma mua i nā wahine postmenopausal, ʻaʻole ʻike ʻia ka lōʻihi o ka lāʻau lapaʻau. I ka hoʻokolokolo ATAC, ua lawelawe ʻia ʻo ARIMIDEX no ʻelima mau makahiki.
ʻAʻole pono ka hoʻoponopono ʻana i ka dosage no nā mea maʻi me ka maʻi renal a i ʻole nā maʻi maʻi ʻelemakule.
He aha kāu e ʻike ai ma mua o kou lawe ʻana i ka pauka Arimidex?
Nā ʻōlelo aʻoaʻo a me nā hana hoʻomalu
E kamaʻilio me kāu kauka, lāʻau lapaʻau, a kahu hānai paha ma mua o ka lawe ʻana iā Arimidex
●inā loaʻa iā ʻoe nā manawa menstrual a ʻaʻole i hele i ka menopause.
●inā ʻoe e lawe ana i ka lāʻau i loaʻa i ka tamoxifen a i ʻole nā lāʻau i loaʻa i ka estrogen (e nānā i ka ʻāpana i kapa ʻia ʻo 'Nā lāʻau ʻē aʻe a me Arimidex').
●inā ua loaʻa iā ʻoe kahi maʻi e pili ana i ka ikaika o kou mau iwi (osteoporosis).
●inā pilikia kou ate a i ʻole nā puʻupaʻa.
Inā ʻaʻole ʻoe maopopo inā pili kekahi o kēia mau mea iā ʻoe, e kamaʻilio me kāu kauka a lāʻau lapaʻau paha ma mua o ka lawe ʻana iā Arimidex.
Inā hele ʻoe i ka haukapila, e ʻike i nā limahana lapaʻau e lawe ana ʻoe iā Arimidex.
ʻO nā lāʻau ʻē aʻe a me Arimidex
E haʻi i kāu kauka a lāʻau lapaʻau paha inā ʻoe e lawe nei a i ʻole ʻoe i lawe i kekahi mau lāʻau lapaʻau ʻē aʻe. Loaʻa kēia i nā lāʻau lapaʻau āu e kūʻai ai me ka ʻole o ka lāʻau lapaʻau. ʻO kēia no ka mea hiki ke hoʻopili ʻo Arimidex i ke ʻano o ka hana ʻana o kekahi mau lāʻau lapaʻau a hiki i kekahi mau lāʻau ke loaʻa ka hopena ma Arimidex.
Mai lawe iā Arimidex inā ʻoe e lawe nei i kekahi o kēia mau lāʻau lapaʻau:
● ʻO kekahi mau lāʻau lapaʻau i hoʻohana ʻia no ka mālama ʻana i ka maʻi maʻi umauma (nā mea hoʻololi o ka estrogen receptor koho), nā lāʻau lapaʻau i loaʻa i ka tamoxifen. ʻO kēia no ka mea hiki i kēia mau lāʻau ke hoʻopau iā Arimidex mai ka hana pono.
● Nā lāʻau i loaʻa i ka estrogen, e like me ka hormone replacement therapy (HRT).
Inā pili kēia iā ʻoe, e nīnau i kāu kauka a lāʻau lapaʻau paha no ka ʻōlelo aʻo.
E haʻi i kāu kauka a lāʻau lapaʻau paha inā ʻoe e lawe nei i kēia:
●Ua ʻike ʻia kahi lāʻau lapaʻau ma ke ʻano he 'LHRH analog'. ʻO kēia ka gonadorelin, buserelin, goserelin, leuprorelin, a me triptorelin. Hoʻohana ʻia kēia mau lāʻau no ka mālama ʻana i ka maʻi maʻi umauma, kekahi mau maʻi olakino wahine (gynecological), a me ka ʻike ʻole.
Hāpai a me ka hānai umauma
Mai lawe ʻoe iā Arimidex inā hāpai ʻoe a hānai paha. E kāpae iā Arimidex inā hāpai ʻoe a kamaʻilio me kāu kauka.
E noi i kāu kauka a kauka paha no ka ʻōlelo aʻo ma mua o ka lawe ʻana i nā lāʻau.
Ke hoʻokele a me ka hoʻohana ʻana i nā mīkini
ʻAʻole pili paha ʻo Arimidex i kou hiki ke hoʻokele a hoʻohana i nā mea hana a me nā mīkini. Eia naʻe, hiki i kekahi poʻe ke manaʻo nāwaliwali a hiamoe paha i ka lawe ʻana iā Arimidex. Inā loaʻa kēia iā ʻoe, e nīnau i kāu kauka a lāʻau lapaʻau paha no ka ʻōlelo aʻo.
Aia ʻo Arimidex i ka lactose
Aia ʻo Arimidex i ka lactose he ʻano kō. Inā ua haʻi ʻia ʻoe e kāu kauka he intolerance ʻoe i kekahi mau kō, e kelepona i kāu kauka ma mua o ka lawe ʻana i kēia lāʻau lapaʻau.
Anastrozole vs.Letrozole
● ʻO Anastrozole a me letrozole nā lāʻau lapaʻau aromatase a me nā lāʻau anti-cancer i hoʻohana ʻia no ka mālama ʻana i nā wahine postmenopausal me ka maʻi kanesa umauma.
● ʻO ka inoa inoa no ka anastrozole ʻo Arimidex a ʻo ka inoa inoa no ka letrozole ʻo Femara. ʻelua loaʻa nā lāʻau lapaʻau ma ke ano ma'amau.
● ʻaoʻao waiwai ʻO anastrozole a me letrozole e like me ka nausea, ka luaʻi, a me ke poʻo.
● ʻaoʻao waiwai ʻO ka anastrozole ka mea ʻokoʻa me ka letrozole, ʻo ia ka wela wela, ka ʻeha, ka ʻāʻī, ka piʻi ʻana o ke koko, ke kaumaha, ka ʻeha iwi, nā iwi nāwaliwali, ka hiamoe ʻole, a me ka ʻūhū.
● ʻaoʻao waiwai ʻO ka letrozole i ʻokoʻa me ka anastrozole, ʻo ia ka luhi, ka ʻeha ʻiʻo, ka maʻi maʻi, constipation, a me ka ʻeha o ka umauma.
● ʻAʻole pono e hoʻohana ʻia nā anastrozole a me ka letrozole me ka tamoxifen no ka mea hiki i ka tamoxifen ke hoʻemi i nā pae anastrozole a me letrozole i loko o ke kino a hoʻemi i kā lākou hopena therapeutic.
Pehea e mālama ai iā Anastrozole (Arimidex) ka lehu?
Mai mālama ma luna o 30 ° C.
E mālama i ka pauka Arimidex mai ka ʻike a hiki i nā keiki. E mālama i kahi palekana kahi hiki ʻole ke ʻike a hiki i nā keiki.
Mai hoolei aku i na laau lapaau ma o ka wai palau a me ka lepo o ka hale. E nīnau i kāu kauka lāʻau pehea e hoʻolei aku ai i nā lāʻau āu e hoʻohana ʻole ai. E kōkua ana kēia mau hana i ka pale ʻana i ke kaiapuni.
Ma hea e kūʻai ai i ka pauka Anastrozole (Arimidex)?
ʻO ka pauka Arimidex, kahi mea hoʻopaneʻe aromatase ikaika a koho i hoʻohana ʻia i ka mālama ʻana i ka maʻi maʻi umauma estrogen-receptor-positive. loaʻa mai nā ʻano mea hoʻolako pūnaewele hilinaʻi. ʻO kekahi mea hoʻolako Arimidex KANAKA, he mea hana kaulana i hoʻolalelale i nā mea waiwai kiʻekiʻe a me nā pūhui kemika. Me ka hoʻolaʻa i ka mana koʻikoʻi a me ka mālama ʻana i nā kūlana ʻoihana, Hoʻomaopopo ʻo AASraw e loaʻa i nā mea kūʻai aku nā huahana maikaʻi loa no ko lakou ola kino. Ma ke koho ʻana e kūʻai i ka pauka Arimidex mai KANAKA, hiki i nā mea kūʻai ke hauʻoli i ka ʻike kūʻai maʻemaʻe, palekana, a hilinaʻi hoʻi, ʻoiai e pōmaikaʻi ana i ka ʻike nui a me ka loea o ka hui ma ka ʻoihana lāʻau.
Inā makemake ʻoe e kūʻai i ka pauka Arimidex nui a kūʻai nui paha, ʻO AASRAW kekahi o nā mea hoʻolako ʻaʻole ʻoe makemake e hala.
Raw Anastrozole(Arimidex) Hōʻike Hōʻike Hōʻike Pahu-HNMR
He aha ka HNMR a he aha ka HNMR spectrum e haʻi iā ʻoe? ʻO H Nuclear Magnetic Resonance (NMR) spectroscopy kahi ʻenehana kemika analytical i hoʻohana ʻia i ka hoʻokele maikaʻi a me ka noiʻi no ka hoʻoholo ʻana i ka ʻike a me ka maʻemaʻe o kahi laʻana a me kona ʻano molekala. No ka laʻana, hiki i ka NMR ke hoʻokaʻawale i nā huila i loaʻa nā pūhui i ʻike ʻia. No nā pūhui i ʻike ʻole ʻia, hiki ke hoʻohana ʻia ka NMR e hoʻohālikelike i nā hale waihona puke spectral a i ʻole e kuhi pololei i ke ʻano kumu. Ke ʻike ʻia ke ʻano kumu, hiki ke hoʻohana ʻia ka NMR no ka hoʻoholo ʻana i ka conformation molecular i ka hopena a me ke aʻo ʻana i nā waiwai kino ma ka pae molekala e like me ka hoʻololi conformational, nā hoʻololi ʻana, ka solubility, a me ka diffusion.
Anastrozole pauka(120511-73-1)-COA
Anastrozole pauka(120511-73-1)-COA
Pehea e kūʻai ai i ka pauka Anastrozole (Arimidex) mai AASraw?
❶E hoʻokaʻaʻike mai iā mākou ma kā mākou ʻōnaehana nīnau leka uila, a i ʻole e waiho i kāu helu WhatsApp, e hoʻopili aku kā mākou mea kūʻai aku (CSR) iā ʻoe i nā hola 12.
❷E hāʻawi iā mākou i kāu helu a me kāu helu wahi i nīnau ʻia.
❸Na kā mākou CSR e hāʻawi iā ʻoe i ka ʻōlelo ʻōlelo, ka manawa uku, ka helu ʻimi, nā ala lawe, a me ka lā i manaʻo ʻia e hiki mai ai (ETA).
❹Hoʻopau ʻia ka uku a hoʻouna ʻia nā waiwai i nā hola 12.
❺ Loaʻa nā waiwai a hāʻawi i nā manaʻo.
Mea kākau o kēia ʻatikala:
Kauka Monique Ua puka 'o Hong mai ke Kula Nui o UK Imperial College London Faculty of Medicine
Mea kākau moʻolelo puke moʻolelo ʻepekema:
1. Kevin H. Nguyen
Ke Kula Nui ʻo Creighton University of Medicine, 7500 Mercy Rd, Omaha, NE, 68124, USA
2. Prof Jack Cuzick PhD
Center for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University London, Lākana, UK
3. Dhairysheel Ghadge
Keʻena ʻOihana Lapaʻau, Gourishankar Institute of Pharmaceutical Education and Research, Limb, 415020, Maharashtra state, India
4. K. Pather
Kula o nā ʻepekema Anatomical, Kumu o nā ʻepekema Ola, Kulanui o Witwatersrand, 7 York Road, Parktown, 2193 Johannesburg, ʻApelika Hema
5. Maria de Pilar Estevez-Diz
Instituto do Cancer do Estado de Sao Paulo – Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil
ʻAʻole ʻae kēia kauka/ ʻepekema i ke kūʻai, kūʻai ʻana, a hoʻohana paha i kēia huahana no kekahi kumu. ʻAʻohe pili a pili ʻole ʻo Aasraw, i hōʻike ʻia a i ʻole, me kēia kauka. ʻO ke kumu o ka haʻi ʻana i kēia kauka, ʻo ia ka hoʻomaikaʻi ʻana a me ka hoʻomaikaʻi ʻana i ka hana noiʻi a me ka hoʻomohala piha i hana ʻia e nā ʻepekema e hana nei i kēia mea.
Reference
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[2] Howell A, Cuzick J, Baum M, Buzdar A, Dowsett M, Forbes JF, et al. (2005). "Nā hopena o ka ho'āʻo ATAC (Arimidex, Tamoxifen, Alone a i ʻole Hui Pū ʻia) ma hope o ka pau ʻana o 5 mau makahiki 'adjuvant lapaʻau no ka maʻi maʻi umauma". Lancet. 365 (9453): 60–2. doi:10.1016/S0140-6736(04)17666-6. PMID 15639680. S2CID 8350282.
[3] Nā Duke M (1997). "Ka pili o nā hiʻohiʻona preclinical i ka mālama ʻana i ka maʻi maʻi umauma postmenopausal". Oncology. 54 Suppl 2 (2): 6–10. doi:10.1159/000227748. PMID 9394853.
[4] Sanford M, Plosker GL (2008). "Anastrozole: kahi loiloi o kona hoʻohana ʻana i nā wahine postmenopausal me ka maʻi maʻi umauma mua". ʻO nā lāʻau lapaʻau. 68 (9): 1319–40. doi:10.2165/00003495-200868090-00007. PMID 18547136.
[5] Simpson ER (Sepatemaba 2003). "Nā kumu o ka estrogen a me ko lākou mea nui". ʻO ka Journal of Steroid Biochemistry and Molecular Biology. 86 (3–5): 225–30. doi:10.1016/S0960-0760(03)00360-1. PMID 14623515. S2CID 11210435.
