ʻO ka pauka Exemestane

ʻO ka pauda Exemestane wikiō-AASraw

ʻO ka pauda Exemestane Nā Kiʻi Kumu

He aha ka Exemestane Powder?

ʻO Exemestane Powder, i kūʻai ʻia ma lalo o ka inoa inoa ʻo Aromasin i waena o nā mea ʻē aʻe, he lāʻau lapaʻau i hoʻohana ʻia e mālama i ka maʻi maʻi umauma. I kekahi mau maʻi maʻi maʻi umauma, hoʻoulu ka estrogen i ka ulu ʻana o nā maʻi kanesa. He ʻoiaʻiʻo kēia ma hope o ka chemotherapy. Hoʻohana ʻia ʻo Aromasin, ma ke ʻano he mea hoʻopaneʻe aromatase, e hoʻemi i ka nui o ka estrogen i loko o ke kino, a laila e kāpae i ka ulu ʻana a i ʻole ka hoʻi ʻana o ka maʻi maʻi umauma.

ʻOiai ua hoʻolālā mua ʻia no nā wahine post-menopausal e hoʻāʻo nei e hoʻopau i ka maʻi kanesa o ka umauma, ʻo ka ʻoiaʻiʻo e hiki i ka Aromasin Powder ke ʻoki i ka hana estrogen ua kaulana loa ia me ka bodybuilding a me nā kaiāulu hoʻohana steroid.

Pehea hana ʻo Exemestane Powder hana?

Hoʻoulu ʻia ka nui o nā maʻi maʻi maʻi maʻi e ulu e nā hormone wahine wahine estrogen a me progesterone. Ua kapa ʻia kēia mau maʻi maʻi maʻi umauma hormone-sensitive a i ʻole hormone receptor-positive. Hiki i ka pale ʻana i nā hopena o kēia mau hormones ke mālama i ka maʻi maʻi umauma.

I loko o nā wahine i loaʻa i ka menopause, hana nui ʻia ka estrogen ma o ka hoʻololi ʻana i nā androgens (nā hormones sex i hana ʻia e nā kelepa adrenal) i estrogens. Kapa ʻia kēia kaʻina hana ʻo ka aromatization a loaʻa nui i nā ʻiʻo momona, nā ʻiʻo, a me ka ʻili. Pono ia i kahi enzyme i kapa ʻia ʻo aromatase.

Hoʻopili ka Exemestane Powder i ke kaʻina hana o ka aromatization. No laila, hoʻohaʻahaʻa ia i ka nui o ka estrogen i loko o ke kino. I ka maʻi maʻi maʻi mua, hiki i ka lawe ʻana i ka Exemestane Powder ke kōkua i ka pale ʻana i ka maʻi maʻi umauma mai ka hoʻi ʻana mai. I ka ma'i 'a'ai ma'i ma'i, hiki i ka ma'i 'a'ai ke ulu lohi a oki loa.

He aha ka Aromasin (Exemestane Powder) hoʻohanaʻia no?

①Ka maʻi maʻi umauma

Hoʻohana ʻia ʻo Aromasin no ka mālama ʻana i ka maʻi maʻi maʻi maʻi o ka maʻi maʻi o ka maʻi maʻi maʻi maʻi i nā wahine menopausal.

Manaʻo pinepine ʻia ʻo Aromasin ma hope o nā lāʻau lapaʻau maʻi maʻi umauma e like me ka chemotherapy, ʻokiʻoki, a i ʻole radiation no ka maʻi maʻi umauma mua, ʻo ia ka maʻi kanesa ʻaʻole i holomua ma waho o ka umauma.

Hoʻohana pū ʻia e mālama i ka maʻi maʻi maʻi maʻi maʻi i laha ma waho o ka umauma ma hope o ka mālama ʻana me ka hormone therapy tamoxifen.

②Hoʻoulu kino

ʻO ka Exemestane Powder ka mea iʻike nuiʻia no ka mālamaʻana i kekahiʻano o ka maʻi kanesa o ka umauma i nā wāhine. Hoʻohaʻahaʻa ia i nā pae estrogen i loko o ke kino e pono ai e nā maʻi maʻi maʻi umauma e ulu. ʻOiai ʻo kēia ka pōmaikaʻi kaulana loa o ka hoʻohana ʻana i ka Exemestane Powder, aia kekahi mau pono Aromasin Powder āu e hauʻoli ai e lawe. ʻO ka huahana kaulanaʻole i nā haʻuki, no ka mea, hiki iā ia ke hoʻopau pono i nā hopena estrogenic o nā steroid anabolic. Ua like kona ʻano hana me nā mea hoʻokae aromatase kaulana loa - Letrozole a Anastrozole, Hoʻohana pinepine nā mea pāʻani i ka Exemestane Powder i ka bodybuilding ma hope o ke kaʻina steroid.

ʻO ka mea mua, ua hoʻohana ʻia ka Exemestane Powder e hoʻomaikaʻi i ka hana ma o ka doping ma o ka hoʻonui ʻana i nā pae o ka hormone luteinizing (LH) a me ka follicle-stimulating hormone (FSH). Hana ʻia kēia ma ka hoʻonui ʻana i ka ratio o nā hormones pili kāne i ka wahine. Hoʻohui, mālama ka lāʻau lapaʻau i ka gynecomastia a hōʻemi i ka wai a me ka hōʻiliʻili momona i lawe ʻia e ka hoʻonui ʻana i ka aromatase i lawe ʻia e ka testosterone doping.

ʻO ka lua, he lāʻau lapaʻau waha kēia, ʻo ia hoʻi, ʻaʻole ʻoe e hālāwai me nā injections i ka wā e lawe ana i kāu mau dosages. He ola ikaika ka huahana o 48 mau hola, a inā e haʻalele ʻoe i kahi dosage Exemestane Powder ʻaʻohe mea e hopohopo ai, pono ʻoe e lawe i ka lā aʻe i ka lā aʻe, a maikaʻi ʻoe e hele. Ua hōʻike pū ʻia nā haʻawina e hiki i ka Exemestane Powder ke kōkua i ka pale ʻana i nā ʻiʻo kino mai ka oxidation a me ka pōʻino ʻeha i nā kāne a me nā wahine. Ma waho aʻe, ua ʻōlelo ʻia ka lāʻau lapaʻau i ka pale ʻana i kou kino mai ka hōʻino ʻana i kā lākou DNA e ka radiation UV i ka wā o ka oxidation. Hoʻohana ʻo Exemestane Powder ma ke ʻano he anti-inflammatory maikaʻi loa.

ʻAʻole paha i loaʻa i ka mea hoʻolale kino kino ka lāʻau Aromasin i kauoha ʻia mai ke kauka no ka mea aia ʻo Exemestane ma ka papa inoa o ka World Anti-Doping Agency o nā mea i pāpā ʻia.

ʻO ka hapa nui o nā bodybuilders e kūʻai iā Aromasin (Exemestane Powder) mai kahi mea hoʻolako pūnaewele. Ke kūʻai aku nei i ka Exemestane Powder ma ka pūnaewele hiki ke kōkua iā lākou e mālama i ke kālā a hoʻokō i kā lākou pono post-cycle therapy. ʻOi aku ka maikaʻi o ke kumukūʻai o Exemestane Powder ma mua o ka lāʻau Aromasin. Hiki iā ʻoe ke kūʻai i ka Exemestane Powder kiʻekiʻe mai ka mea hana AASRAW.

Pehea e hoʻohana ai i ka Aromasin? ʻO Exemestane Powder alakaʻi kuhikuhi

Ke nānā aku nei nā mea hoʻohana steroid i ka hoʻohui ʻana me ka Aromasin Powder i ka wā a ma hope koke o kahi pōʻai.

Ma hope o ka synthetically supplementing no ka pōʻaiapuni, e emi loa ana kāu hana maoli o ka testosterone a pono kou kino i ka manawa e hoʻomaka hou i kāu hana testosterone. I kēia manawa, e nānā ana ka estrogen e hoʻi hou. ʻO kēia kahi e hiki ai i kahi PCT Extremestane Powder ke kōkua.

ʻO ka hoʻohana ʻana i kahi PCT Aromasin Powder me ka ʻole o nā steroid anabolic e kōkua i ka mālama ʻana i nā pae estrogen i ka lōʻihi no kāu hana ponoʻī o ka testosterone e hoʻihoʻi ʻia. Mālama kēia iā ʻoe e pale i nā hopena ʻaoʻao gyno-based o nā steroid anabolic e like me ka boobs man.

Pono ʻoe e lawe i ka Aromasin (ʻo ka mea hana ʻo Exemestane Powder) e like me ka ʻōlelo a kāu kauka. E hahai i nā kuhikuhi a pau ma kāu lepili lāʻau a heluhelu i nā alakaʻi lāʻau a i ʻole nā ​​pepa kuhikuhi. Aia ma waena o 10mg a 25mg ka nui o nā mea hou e nānā ana i nā dosages ma waena o 10mg a 15mg.

Inā loaʻa iā ʻoe ka ʻike waiwai i ka hoʻohana ʻana i ka Aromasin, hiki iā ʻoe ke kūʻai aku i ka mea hoʻohana ʻo Exemestane Powder ma ka pūnaewele. ʻO ka dosage Exmestane Powder ka like me ka lāʻau Aromasin. Nui nā Exemestane Powder no ke kūʻai aku ma ka pūnaewele, maʻalahi ke kiʻi. Akā no ka loaʻa ʻana o kahi mea hana Exemestane Powder maikaʻi, pono ʻoe e hoʻolei i kāu hana i loko, ʻaʻole hiki ke hilinaʻi ʻia nā pūnaewele Exemestane Powder āpau. Eia naʻe, hiki iā ʻoe ke kūʻai mai iā AASRAW mea hoʻolako. ʻO AASRAW kahi hale hana Exemestane Powder maoli e hiki ke hoʻolako i ka Exemestane Powder wholesale. Inā makemake ʻoe e mālama i kekahi kumukūʻai ma ka mālama ʻana iā Aromasin, hiki iā ʻoe ke kūʻai i ka Exemestane Powder wholesale e kiʻi i ke kumu kūʻai.

He aha nā hopena ʻaoʻao o ʻO'Aromana?

Hiki i ka Aromasin Powder ke hana i nā hopena koʻikoʻi e like me:

• ʻeha iwi hou a ʻokoʻa paha,
• ka pehu ma kou mau lima a me kou mau wāwae,
• ʻaʻohe hanu,
• ʻeha ka ʻōpū,
• nawaliwali koke,
• poʻo koke,
• huikau, a
• pilikia me ka ʻike, ka ʻōlelo, a i ʻole ke kaulike
• E kiʻi koke i ke kōkua olakino, inā loaʻa iā ʻoe kekahi o nā hōʻailona i helu ʻia ma luna.
• ʻO nā hopena ʻaoʻao maʻamau o ka AromasinPowder penei:
• wela wela,
• nā maʻiʻeha,
• luhi luhi,
• ʻeha pū,
• Nausea,
• hoʻonui i ka ʻai,
• pilikia moe (insomnia), a
• hoʻonui hoʻonui ʻia

E haʻi i ke kauka inā loaʻa iā ʻoe kekahi hopena ʻaoʻao e hoʻopilikia iā ʻoe a ʻaʻole e hele.

ʻAʻole kēia nā hopena ʻaoʻao āpau o ka Aromasin Powder. No ka ʻike hou aku, e nīnau i kāu kauka a lāʻau lapaʻau paha.

Kāhea i kāu kauka no ka'ōlelo aʻo kino no nā hopenaʻaoʻao.

Kahi e kūʻai Pāwehe (ʻO'Aromana) Powder nui?

I ka honua hou, hiki iā ʻoe ke kūʻai i ka Exemestane Powder i ka nui ma ka pūnaewele a i ʻole mai kekahi lāʻau lapaʻau a puni ʻoe, akā e mālama pono ʻaʻole ʻoe e hoʻomaka e lawe me ka ʻole o ka ʻōlelo aʻo a kāu kauka. E hōʻoia e kūʻai ʻoe i ka Exemestane Powder mai kahi mea hana kaulana a mea hoʻolako paha no nā hopena maikaʻi aʻe. ʻAʻole hiki ke hilinaʻi ʻia nā mea hoʻolako Exemestane Powder āu e ʻike ai ma ka pūnaewele. ʻO nā loiloi mea kūʻai aku kahi ala e hōʻoiaʻiʻo ai i nā pono o ka Aromasin Powder a hōʻiliʻili pū i ka ʻike e pili ana i nā hopena ʻaoʻao. ʻO kahi ʻē aʻe, hiki iā ʻoe ke kumu no nā mea hoʻolako nui ʻo Aromasin Powder i ʻae ʻia e kūʻai aku i kēia mau mea hoʻohui.

E noʻonoʻo e kūʻai i ka Exemestane Powder i ka nui nui e leʻaleʻa i nā uku ma laila.

ʻO ka pauda Exemestane Hoike Hoao-HNMR

He aha ka HNMR a he aha ka HNMR spectrum e haʻi iā ʻoe? ʻO H Nuclear Magnetic Resonance (NMR) spectroscopy kahi ʻenehana kemika analytical i hoʻohana ʻia i ka hoʻokele maikaʻi a me ka noiʻi no ka hoʻoholo ʻana i ka ʻike a me ka maʻemaʻe o kahi laʻana a me kona ʻano molekala. No ka laʻana, hiki i ka NMR ke hoʻokaʻawale i nā huila i loaʻa nā pūhui i ʻike ʻia. No nā pūhui i ʻike ʻole ʻia, hiki ke hoʻohana ʻia ka NMR e hoʻohālikelike i nā hale waihona puke spectral a i ʻole e kuhi pololei i ke ʻano kumu. Ke ʻike ʻia ke ʻano kumu, hiki ke hoʻohana ʻia ka NMR no ka hoʻoholo ʻana i ka conformation molecular i ka hopena a me ke aʻo ʻana i nā waiwai kino ma ka pae molekala e like me ka hoʻololi conformational, nā hoʻololi ʻana, ka solubility, a me ka diffusion.

Pahu Exemestane(107868-30-4)-COA

Pahu Exemestane(107868-30-4)-COA

Pehea e kūʻai ʻO ka pauda Exemestane mai AASraw?

❶E hoʻokaʻaʻike mai iā mākou ma kā mākou ʻōnaehana nīnau leka uila, a i ʻole e waiho i kāu helu WhatsApp, e hoʻopili aku kā mākou mea kūʻai aku (CSR) iā ʻoe i nā hola 12.

❷E hāʻawi iā mākou i kāu helu a me kāu helu wahi i nīnau ʻia.

❸Na kā mākou CSR e hāʻawi iā ʻoe i ka ʻōlelo ʻōlelo, ka manawa uku, ka helu ʻimi, nā ala lawe, a me ka lā i manaʻo ʻia e hiki mai ai (ETA).

❹Hoʻopau ʻia ka uku a hoʻouna ʻia nā waiwai i nā hola 12.

❺ Loaʻa nā waiwai a hāʻawi i nā manaʻo.

Mea kākau o kēia ʻatikala:
Kauka Monique Ua puka 'o Hong mai ke Kula Nui o UK Imperial College London Faculty of Medicine

Mea kākau moʻolelo puke moʻolelo ʻepekema:
1.Reza Hoseinpour Kouhestany
Keʻena ʻOihana Kimia, Central Tehran Branch, Islamic Azad University, Tehran, Iran
2.Marta S. Laranjeira
i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen 208, 4200-135 Porto, Pokukala
3.Patricia A. Opio MD
Māhele o Hematology-Oncology, Keʻena ʻOihana Lapaʻau, UCLA David Geffen School of Medicine, Los Angeles, Kaleponi
4.Ana Filipa Sobral
Kumu o ka ʻepekema a me ka ʻenehana, Kulanui o Coimbra, Calçada Martim de Freitas 3000-456 Coimbra, Pokukala
5. Lesley J. Scott
Adis International Limited, 41 Centorian Drive, ʻeke pilikino 65901, Mairangi Bay, Auckland, 10, New Zealand
ʻAʻole ʻae kēia kauka/ ʻepekema i ke kūʻai, kūʻai ʻana, a hoʻohana paha i kēia huahana no kekahi kumu. ʻAʻohe pili a pili ʻole ʻo Aasraw, i hōʻike ʻia a i ʻole, me kēia kauka. ʻO ke kumu o ka haʻi ʻana i kēia kauka, ʻo ia ka hoʻomaikaʻi, hoʻomaikaʻi a hoʻomaikaʻi i ka hana noiʻi a me ka hoʻomohala piha i hana ʻia e nā ʻepekema e hana nei i kēia mea.

E hoʻomaopopo '

[1] D Clemett, HM Lamb. "Exemestane: he loiloi o kona hoʻohana ʻana i nā wahine postmenopausal me ka maʻi maʻi umauma kiʻekiʻe" 2000 Jun; 59 (6): 1279-96. doi: 10.2165/00003495-200059060-00007.PMID: 10882163

[2] Clemett D, Lamb HM. Exemestane: he loiloi o kona hoʻohana ʻana i nā wahine postmenopausal me ka maʻi maʻi umauma kiʻekiʻe. Nā lāʻau lapaʻau. 2000 Iun;59(6):1279-96. doi: 10.2165/00003495-200059060-00007. PMID: 10882163

[3] Scott LJ, Wiseman LR. Exemestane. Nā lāʻau lapaʻau. 1999 ʻOkakopa;58(4):675-80; kūkākūkā 681-2. doi: 10.2165/00003495-199958040-00007. PMID: 10551437

[4] Decensi A, Dunn BK, Puntoni M, Gennari A, Ford LG. Exemestane no ka pale ʻana i ka maʻi maʻi umauma: kahi hoʻololi koʻikoʻi? ʻO ka Discov. 2012 Jan;2(1):25-40. doi: 10.1158/2159-8290.CD-11-0248. PMID: 22585166

[5] Wang Y, Jing F, Wang H. Role of Exemestanein the treatment of Estrogen-Receptor-Positive Breast Cancer: He Narrative Review of Recent Evidence. Adv Ther. 2022 Feb;39(2):862-891. doi: 10.1007/s12325-021-01924-2. Epupa 2022 Jan 6. PMID: 34989983

[6] Tahara M, Nomura S, Hashimoto M. [Pharmacological and clinical profile of Exemestane (Aromasin), he novel irreversible aromatase inhibitor]. Nihon Yakurigaku Zasshi. 2003 ʻOkakopa;122(4):345-54. doi: 10.1254/fpj.122.345. PMID: 14501171

E kiʻi i kahi hōʻaiʻē nui