Letrozole pauda

Letrozole Makaʻu (Femara) Powder Nā Kiʻi Kumu

He aha ka Letrozole Powder?

ʻO Letrozole Powder kahi anti-estrogen a me kekahi o nā mea hoʻopiʻi Aromatase ikaika loa. Kūʻai pinepine ʻia ma lalo o ka inoa inoa Femara ma waena o nā mea ʻē aʻe. I kēia manawa, hoʻohana ʻia e nā bodybuilders he nui i ka wā post-cycle therapy (PCT) a hoʻokō i nā steroid anabolic a i ʻole prohormones. Kōkua ʻo Letrozole Powder i ke kino e hoʻi i kona pae maʻamau a hoʻopaʻa i nā pae hormonal.

Pehea e hoʻonui ai ka hana ʻana o Letrozole?

ʻO ka pauka Letrozole he mea hoʻomakeʻa aromatase, ʻo ia hoʻi e poloka ia i kahi enzyme kuleana no kahi hana nui i ka hoʻokumu ʻana o nā estrogens. ʻOi aku ka kikoʻī, ʻo ka enzyme aromatase ke kuleana no ka hoʻololi ʻana o nā androgens (eg, testosterone) i estrogens. Letrozole keʻakeʻa i kēia kaʻina hana, e hoʻemi ana i ka nui o ka estrogen i loko o ke kino.

Aia ʻo Letrozole i ka lāʻau lapaʻau i hoʻohana ʻia no ka hakakā ʻana i ka maʻi kanesa o ka umauma e pili ana i ka estrogen i nā wahine. Ma ka ho'ēmiʻana i ka nui o ka estrogen i loko o ke kino, hiki i ka letrozole ke ho'ēmi a ho'ōki paha i ka uluʻana o kekahiʻano o nā maʻi maʻi maʻi umauma e pono ai ka estrogen e ulu.

Hoʻohana ʻia ka pauka Letrozole no ka mālama ʻana i ka maʻi maʻi umauma mua i nā wahine i loaʻa i ka menopause (hoʻololi o ke ola, ka hopena o nā manawa menstrual mahina) a i loaʻa i nā lāʻau lapaʻau ʻē aʻe, e like me ka radiation a i ʻole ke ʻoki ʻana e wehe i ke koko. Hoʻohana ʻia e mālama i ka maʻi maʻi umauma mua i nā wahine i ʻike i ka menopause a ua mālama ʻia me kahi lāʻau i kapa ʻia ʻo tamoxifen (Nolvadex) no 5 makahiki. Hoʻohana pū ʻia ʻo Letrozole i nā wahine i loaʻa i ka menopause ma ke ʻano he lapaʻau mua o ka maʻi maʻi umauma i laha i loko o ka umauma a i ʻole i nā wahi ʻē aʻe o ke kino a i nā wahine i ʻoi aʻe ka maʻi maʻi umauma i ko lākou lawe ʻana i ka tamoxifen. Aia ʻo Letrozole i kahi papa o nā lāʻau i kapa ʻia ʻo nonsteroidal aromatase inhibitors. Hana ia ma ka hoʻemi ʻana i ka nui o ka estrogen i hana ʻia e ke kino. Hiki i kēia ke hoʻolohi a hoʻōki paha i ka ulu ʻana o kekahi mau ʻano o ka maʻi maʻi umauma e pono ai ka estrogen e ulu.

Nā pono o ka pauda Letrozole no nā kāne

No kekahi mau mea hoʻohana, ʻo Letrozole Powder, Clomid, a me Nolvadex kahi hihia o ka hoʻohālikelike ʻana i nā ʻāpala a me nā ʻalani. ʻOiai ʻo ia ka mea like, he ʻokoʻa nā hopena, nā lōʻihi, a me nā hopena.

Inā hopohopo ʻoe e pili ana i ka gyno, a laila ʻoi aku ka maikaʻi o ka Letrozole Powder. He wahie nukili ia no nā mea hoʻohana steroid e loaʻa ana i ka gyno, a hiki iā ia ke hoʻohuli i nā hōʻailona.

He koho maikaʻi loa nā SERM no ka hoʻihoʻi ʻana i nā pae testosterone. E hoʻihoʻi ʻo Clomid a i ʻole Nolvadex i kāu mau pae ma kahi o 60% mai ka papa kuhikuhi i loko o hoʻokahi mahina. No ka hoʻihoʻi maʻamau, ʻoi aku ka maikaʻi ma mua o ka Letrozole Powder.

Ma keʻano he bodybuilder, hiki ke nani nā pono o ka Letrozole Powder no ka mea,ʻaʻole wale ia e pale i kēia hoʻololi a no laila e ho'ēmi i ka nui o ka estrogen i ka wā eʻae ai i ka testosterone e piʻi aʻe, akā hiki iā ia ke pale i ka paʻaʻana o ka wai e alakaʻi ai i kahi nānā paʻakikī a maloʻo i kou kino muscle. . E hoʻomanaʻo, e kūʻai mau i ka Letrozole Powder kiʻekiʻe, ʻo ia ke ʻano o ka loaʻa ʻana o nā pono Letrozole Powder i ʻōlelo ʻia. AASraw Letrozole Powder mea hoʻolako, e kelepona mai iā mākou i kēia manawa.

Ma keʻano holoʻokoʻa, ua loaʻa iaʻu kahi ʻike nui e hoʻohana ana i ka Letrozole Powder no PCT, a ma ka pūnaewele, nui nā kamaʻilio maikaʻi e pili ana i nā pono o Letrozole Powder e hoʻohana pū ana.

Aia kekahi ʻano kūʻē e huikau ai i ka poʻe, ʻo ia ka mea e hoʻopau pinepine ai nā mea hoʻonā aromatase i ka hoʻololi ʻana, ʻoiai ʻoi aku ka maikaʻi o ka SERM i ka huli ʻana i nā mea loaʻa estrogen i kekahi mau kiko, ʻoi aku ka umauma. Eia nō naʻe, ma waena o nā bodybuilders, ʻike ʻia ʻo AASraw Letrozole Powder i mea maikaʻi loa no ka gyno, ke manaʻo ʻoe he ʻoiaʻiʻo ka ʻaoʻao a ʻo Nolvadex / Clomid.

Manaʻo wau he aha ka mea nui e pili ana i ka ikaika loa i nā koina kiʻekiʻe, ʻoi aku ka ikaika o nā hopena maʻamau a pani lākou i ka holomua gyno, a hiki ke hoʻohuli. Ma ka ʻaoʻao ʻē aʻe, hiki i ka Nolvadex a me Clomid ke ikaika, akā ʻaʻole lākou e kīkī me ka ikaika a mālama i ka hoʻomaka, e hāʻawi ana i ka manawa no ka gyno e holomua.

Nā hopena ʻaoʻao o Letrozole pauda?

Hiki i nā hopena ʻaoʻao maʻamau ke like me nā hōʻailona menopause a loaʻa i nā uila wela, pilikia ka hiamoe, luhi, a me ke ʻano haʻahaʻa. Hoʻonui pinepine ʻia nā hopena ʻaoʻao ma hope o kekahi mau mahina ke hoʻomaʻamaʻa kou kino i ka lāʻau. Na kāu kauka e nānā i kou kahe koko, ka pae cholesterol, a me ka iwi iwi i ka wā o kāu mālama ʻana.

Ka Papahana o Letrozole Pauda

①Letrozole Dosage I ka Hoʻohana Anabolic Steroid

ʻO ka hana hewa ʻana o ka lawe nui ʻana i ka Letrozole Powder i ka wā o ka hoʻohana ʻana i ka steroid ʻaʻole ia he pōmaikaʻi a lawe mai i nā hopena maikaʻi ʻole, e like me ka luhi, ʻOiaʻiʻo, he mea nui ke kūʻai ʻana i ka pauka Letrozole (Femara) kiʻekiʻe. No laila he mea koʻikoʻi ka mālama ʻana i kahi ʻano letrozole Powder kūpono.

Me ka lāʻau lapaʻau maʻamau ma kahi o 2.5mg i kēlā me kēia lā, ʻaʻole mākou e nānā i kahi kiʻekiʻe ma mua o kēlā a ʻo ka hapa nui o ka manawa i lalo. No ka paleʻana i nā hopena pili i ka estrogen i ka wā o ka steroid e hoʻohana i ka nui o ka haʻahaʻa e like me ka 0.5mg a hiki i ka 1.25mg i kēlā me kēia lāʻelua e lawa pinepine no ka palekana pili estrogenic maikaʻi no ka hapanui o nā kāne.

Inā wale ʻoe e ʻike i nā hōʻailona mua o ka gynecomastia e hoʻonui i ka nui i kēia manawa a hiki i ka 2.5mg i kēlā me kēia lā hiki ke hoʻohuli piha i nā hōʻailona, ​​​​akā e mākaukau no kahi zap i ʻike ʻia i kēia manawa. I ka wā e emi ai nā hōʻailona gyno he mea nui ia e hōʻemi i kāu dosage Letrozole Powder i lalo i nā pae palekana estrogenic maʻamau.

②Nā Wahine Letrozole Pauda

ʻO ka piʻi ʻana o nā pae estrogen ʻaʻole ma kahi kokoke i kahi hopohopo nui no nā mea hoʻohana steroid wahine e like me nā kāne. ʻO ke kumu nui o ka hoʻohana ʻana i ka aromatase Inhibitor e like me Letrozole Powder e nā wahine e hoʻēmi i ka paʻa ʻana o ka wai, ʻoi aku hoʻi no nā bodybuilders hoʻokūkū a i ʻole nā ​​​​mea pāʻani kino kahi mea nui loa.

ʻO kaʻoiaʻiʻo,ʻaʻole i'ōleloʻia ka Letrozole Powder ma keʻano he koho mua no nā wāhine ma muli o kona mana e ho'ēmi i ka estrogen nui, no laila ke kumu i hoʻohanaʻoleʻia ai ka lāʻau lapaʻau e nā wāhine i heleʻole i ka menopause. ʻO nā wahine i hoʻoholo i ka hoʻohana ʻana i ka Letrozole Powder e ʻōlelo ʻia e kau ʻia ma ka 0.5mg wale nō i kēlā me kēia lā a e ana i nā hopena a me nā hopena mai laila.

ʻO ka pauka Letrozole vs Clomid vs Arimidex no PCT

ʻO Letrozole Powder Clomid pauka a me Arimidex pauka he mau mea like loa. ʻO nā meaʻelua nā mea hoʻopaneʻe aromatase nonsteroidal a ua makemakeʻiaʻelua e nā mea hoʻohana steroid anabolic e pale i nā hopena o ka estrogenic. Loaʻa i nā lāʻau ʻelua ke ʻano like ʻole o ka hopena. Mai loko mai o kēia mau AI ʻekolu, Arimidex ke alakaʻi nei ma ke ʻano he mea hoʻohana nui ʻia e nā bodybuilders akā hiki ke hele i lalo i nā kumu he nui e pili ana i ka loaʻa, ke kumukūʻai, a me ka makemake e hahai ma ke ala o ka mea a nā hoaaloha a me nā hoa pili pūnaewele e ʻōlelo ai.

ʻOiai hiki i kēia mau AI ʻelua ke kōkua i ka hoʻoulu ʻana i ka hana testosterone kūlohelohe, ʻaʻole i manaʻo ʻia e ka hapa nui o nā kāne ke koho kūpono no PCT ke hoʻohana wale ʻia; ʻoiaʻiʻo, ʻaʻole nui ka poʻe e hoʻohana i kahi AI ikaika e like me Arimidex a i ʻole Letrozole Powder i ka wā PCT i nā mea a pau, a ma kahi o ka hele ʻana i kahi lāʻau SERM me Nolvadex he koho kaulana, me Clomid a pinepine HCG pū kekahi.

ʻO ke kumu nui o kēia ʻo Arimidex maikaʻi loa i ka hoʻohaʻahaʻa ʻana i ka estrogen, a ʻoi aku ka nui o Letrozole. He ikaika loa lākou i kēia hana a hiki iā lākou ke hopena i nā pae estrogen i haʻahaʻa loa no ke kino kāne.

Clomid (clomiphene citrate) ka pauka kekahi lāʻau lapaʻau i hoʻohana pinepine ʻia e nā mea hoʻohana steroid. ʻAʻole like me ka Letrozole Powder he mea hoʻomakeʻa aromatase, ʻo Clomid kahi mea koho estrogen receptor modulator (SERM). He maikaʻi loa nā lāʻau ʻelua akā ʻokoʻa ka hana, no laila ʻaʻole hiki ke ʻōlelo ʻia ʻoi aku ka maikaʻi ma mua o kekahi.

Inā makemake ʻoe i kahi mea hoʻopaneʻe aromatase, ʻo Letrozole Powder ka mea maikaʻi loa i ka hoʻomalu ʻana i nā hōʻailona estrogen i ka wā e noho ana ʻoe ma ka pōʻai steroid ʻoiai ʻo Clomid kahi koho maʻamau no ka hoʻohana ʻana i ka PCT. He mea maikaʻi ʻo Letrozole Powder i ka hoʻohaʻahaʻa ʻana i ka estrogen holoʻokoʻa no laila maikaʻi loa ia no ka mālama ʻana i ka wai a me ka gyno, ʻoiai ʻo Clomid e kuhikuhi pono i ka ʻiʻo o ka umauma.

No ka hoʻohana ʻana iā PCT, ua manaʻo ʻia ʻo Clomid he koho ʻoi aku ka maikaʻi no ka mea ʻaʻole ia e kāohi i nā pae estrogen holoʻokoʻa e like me ka hana a Letrozole e hāʻawi ai i kahi kaulike hormonal maikaʻi no ka hoʻihoʻi ʻana i kāu hana testosterone maʻamau ma hope o ka pōʻaiapuni steroid. Ma ka hoʻohālikelikeʻana, ua manaʻo nuiʻia ka Letrozole Powder e like me ka lāʻau hoʻohaʻahaʻa estrogen e lilo i koho maikaʻi no PCT.

Ma hea e kūʻai ai i ka pauka Letrozole?

ʻO ka pauka Letrozole paha ka mea hoʻomakeʻa aromatase ikaika loa no ka pale ʻana i ka gyno a ʻo ia kāu pahuhopu hope loa: e hoʻōki i ke ʻano mai ka hoʻomaka ʻana e hoʻomohala i nā mea āpau ke hoʻohana nei ʻoe i nā steroid. ʻOi aku ka maikaʻi o ka pale ʻana ma mua o ka mālama ʻana i ka gyno, akā inā ʻike ʻoe e hoʻomaka ana ʻoe e loaʻa i kēlā mau hōʻailona mua a laila ua hoʻōki ʻo Letrozole iā lākou a hoʻohuli iā lākou.

KANAKA ʻO ka manaʻo e hana a hoʻolako i nā mea waena kemika a me nā mea lāʻau lapaʻau ikaika (API), he mea hilinaʻi i ka pauka Letrozole kiʻekiʻe a me nā huahana pili ʻē aʻe. ʻO kā lākou kūpaʻa i ka mana koʻikoʻi a me ka mālama ʻana i nā kūlana ʻoihana e hōʻoia i ka loaʻa ʻana o nā mea kūʻai aku i nā huahana maikaʻi loa no ko lākou olakino a maikaʻi. Ma ke kūʻai ʻana ma AASraw, hiki i nā poʻe e ʻimi ana i ka pauka Letrozole ke hauʻoli i kahi ʻike kūʻai kūpono, palekana, a hilinaʻi hoʻi, ʻoiai e pōmaikaʻi ana i ko lākou ʻike nui a me ka ʻike ma ke kula.

Letrozole(Femara) Powder Hoike Hoao-HNMR

He aha ka HNMR a he aha ka HNMR spectrum e haʻi iā ʻoe? ʻO H Nuclear Magnetic Resonance (NMR) spectroscopy kahi ʻenehana kemika analytical i hoʻohana ʻia i ka hoʻokele maikaʻi a me ka noiʻi no ka hoʻoholo ʻana i ka ʻike a me ka maʻemaʻe o kahi laʻana a me kona ʻano molekala. No ka laʻana, hiki i ka NMR ke hoʻokaʻawale i nā huila i loaʻa nā pūhui i ʻike ʻia. No nā pūhui i ʻike ʻole ʻia, hiki ke hoʻohana ʻia ka NMR e hoʻohālikelike i nā hale waihona puke spectral a i ʻole e kuhi pololei i ke ʻano kumu. Ke ʻike ʻia ke ʻano kumu, hiki ke hoʻohana ʻia ka NMR no ka hoʻoholo ʻana i ka conformation molecular i ka hopena a me ke aʻo ʻana i nā waiwai kino ma ka pae molekala e like me ka hoʻololi conformational, nā hoʻololi ʻana, ka solubility, a me ka diffusion.

Letrozole Pauda(112809-51-5)-COA

Letrozole Pauda(112809-51-5)-COA

Pehea e kūʻai ai i ka Letrozole (Femara) Powder mai AASraw?

❶E hoʻokaʻaʻike mai iā mākou ma kā mākou ʻōnaehana nīnau leka uila, a i ʻole e waiho i kāu helu WhatsApp iā mākou, e hoʻopili aku kā mākou mea kūʻai aku (CSR) iā ʻoe i nā hola 12.

❷E hāʻawi iā mākou i kāu helu a me kāu helu wahi i nīnau ʻia.

❸Na kā mākou CSR e hāʻawi iā ʻoe i ka ʻōlelo ʻōlelo, ka manawa uku, ka helu ʻimi, nā ala lawe, a me ka lā i manaʻo ʻia e hiki mai ai (ETA).

❹Hoʻopau ʻia ka uku a hoʻouna ʻia nā waiwai i nā hola 12.

❺ Loaʻa nā waiwai a hāʻawi i nā manaʻo.

Mea kākau o kēia ʻatikala:
Kauka Monique Ua puka 'o Hong mai ke Kula Nui o UK Imperial College London Faculty of Medicine

Mea kākau moʻolelo puke moʻolelo ʻepekema:
1. Hope S. Rugo
Ke Kulanui o Kaleponi San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA
2. Tara Shochet
Nā Papahana Ola Ola o Gynuity, New York, NY, United States
3. Mehmet Bugra Kivrak
Keʻena o Obstetrics a Gynecology, Kumu o ka Lapaʻau Veterinary, Sivas Cumhuriyet University, Sivas, Turkey
4. Nathalie Søderhamn Bülow
The Fertility Clinic, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, Copenhagen DK-2100, Denmark
5. Tomoko Kuroda MD, Ph.D
Kato Ladies Clinic, Tokyo, Iapana
ʻAʻole ʻae kēia kauka/ ʻepekema i ke kūʻai, kūʻai ʻana, a hoʻohana paha i kēia huahana no kekahi kumu. ʻAʻohe pili a pili ʻole ʻo Aasraw, i hōʻike ʻia a i ʻole, me kēia kauka. ʻO ke kumu o ka haʻi ʻana i kēia kauka, ʻo ia ka hoʻomaikaʻi, hoʻomaikaʻi a hoʻomaikaʻi i ka hana noiʻi a me ka hoʻomohala piha i hana ʻia e nā ʻepekema e hana nei i kēia mea.

E hoʻomaopopo '

[1] Lee VC, Gao J, Lee KF, a me al. ʻO ka hopena o ka letrozole me ka misoprostol no ka hoʻopau lāʻau o ka hāpai ʻana ma ka hōʻike ʻana o nā mea hoʻokipa steroid i ka placenta. Hum Reprod. 2013 Nov;28(11):2912-9. PMID: 23980056.

[2] ʻO Tomao F, Spinelli G, Vici P, a me al. ʻO ka hana o kēia manawa a me ka ʻike palekana o nā mea hoʻopaneʻe aromatase i ka maʻi maʻi umauma mua. Ka loea Rev Anticancer Ther. 2011 ʻAukake;11(8):1253-63. PMID: 21916579.

[3] Yapura J, Mapletoft RJ, Pierson R, a me al. He kumu hoʻohālike pipi no ka nānā ʻana i nā hopena o kahi mea hoʻopaneʻe aromatase i ka hana ovarian i nā wahine. Manuʻa momona. 2011 ʻAukake;96(2):434-438.e3. PMID: 21696721.

[4] Aromatase overexpression transgenic mice model: cell type specific expression and hoʻohana i ka letrozole e hoʻopau i ka hyperplasia mammary me ka ʻole o ka pili ʻana i ka physiology maʻamau. Mandava U, Kirma N, Tekmal RR. J Steroid Biochem Mol Biol. 2001 Dek;79(1-5):27-34.

[5] Hoʻohālikelike lāʻau lapaʻau lāʻau lapaʻau a me pharmacokinetic pilina o ka aromatase inhibitors. Boeddinghaus IM, Dowsett M. J Steroid Biochem Mol Biol. 2001 Dek;79(1-5):85-91.

E kiʻi i kahi hōʻaiʻē nui