Hana ʻo AASraw i nā pauka NMN a me NRC i ka nui!

ʻO ka'openaʻo Lorcaserin (Belviq)

Rating: SKU: 616202-92-7. Māhele:

ʻO ka AASraw me ka hōʻano a me ka hana hana mai ka gram a ka papa hana nui o ka pauka Lorcaserin (Belviq) (616202-92-7), ma lalo o ke kānāwai CGMP a me ke kikowaena o ka mana o ka mana.

Product Description

 

'Ōlelo Hoʻomakaʻo Lorcaserin

ʻO ka hanaʻana i kahi lāʻau lapaʻau kūpono maikaʻi a palekana kahi hana koʻikoʻi. Loaʻa nā ho'āʻo i nā manawa i hala aku me nā hopena e like me ka pōʻino o ka naʻau. ʻO kaʻoluʻolu, ua'ōlelo hou kahi noi hou e hiki i ka pilikino paʻakikī kaumaha ke kōkua iāʻoe e hoʻokahe i ka kaumaha nui me kaʻole e kaumaha i ke ola o kou puʻuwai. ʻO Lorcaserin kahi mea hoʻopiʻi nui loa i ka pill, i'āponoʻia e FDA ma 2012. Akā he aha ka lorcaserin? Ma lalo, heʻike hohonu kahi o ka lāʻau lapaʻau, kona hanana me kona mau waiwai, hoʻohana, hana, mālama, a nui aku.

Mea huahana: Lorcaserin / BELVIQ (lorcaserin hydrochloride)

IUPAC Name: (5R)-7-chloro-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

 

Lorcaserin (Belviq) wikiō paukū

 

 


 

I.Wahahewa (Belviq) nā mea maʻamau:

 

Name: ʻO ka lekaʻo Lorcaserin (Belviq)
CAS: 616202-92-7
Kaulike Molecular:  C11H14ClN
Kaumaha Molecular: 195.692
Wahi Manaʻo: 212 ° C
Hōʻoia Kōkua: RT
kala like 'ole: ʻO ka'ōmaʻomaʻo i ka paukūʻeleʻele

 


 

'Ōlelo Hoʻomakaʻo Lorcaserin

ʻO ka hanaʻana i kahi lāʻau lapaʻau kūpono maikaʻi a palekana kahi hana koʻikoʻi. Loaʻa nā ho'āʻo i nā manawa i hala aku me nā hopena e like me ka pōʻino o ka naʻau. ʻO kaʻoluʻolu, ua'ōlelo hou kahi noi hou e hiki i ka pilikino paʻakikī kaumaha ke kōkua iāʻoe e hoʻokahe i ka kaumaha nui me kaʻole e kaumaha i ke ola o kou puʻuwai. ʻO Lorcaserin kahi mea hoʻopiʻi nui loa i ka pill, i'āponoʻia e FDA ma 2012. Akā he aha ka lorcaserin? Ma lalo, heʻike hohonu kahi o ka lāʻau lapaʻau, kona hanana me kona mau waiwai, hoʻohana, hana, mālama, a nui aku.

Mea huahana: Lorcaserin / BELVIQ (lorcaserin hydrochloride)

IUPAC Name: (5R)-7-chloro-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

 

Ma lalo iho nei ka hale hanaʻeleʻele o ka lorcaserin ma ka 3-D paʻakikī.

ʻO ka lekaʻo Lorcaserin (Belviq)

 

Nā Pono Kemika o Lorcaserin (belviq) (CAS 616202-92-7)

Ma lalo ka hōʻuluʻulu waiwai kemika o Lorcaserin (belviq); ua hōʻike ʻia i ka papa ma lalo nei no ka nānā koke ʻana.

 

Kahi inoa ʻO ka waiwai waiwai
Ka Heluhelu Pāʻokoʻa Pākahi 1
Hoʻomākaukauʻo Isotope Atom 0
Ka helu helu hōʻemiʻole 0
Ka Heluhelu Hoʻohālike Bond Bond 0
ʻO ka heluʻo Atom Stereocenter 0
Hoʻomākaukau'Āina Atom 1
Heluhelu Atomona Heavy 13
Kāleka Kūikawā 0
Hoʻohanaʻia ke Kōmike oiaio
XLogP3-AA 2.7
ʻIke kūpono 195.081 g / mole
Monoisotopic Mass 195.081 g / mole
Wahi Aʻe Pola 12 A '2
Ka nui 172
Ka Helu Helu Lākiō 0
Waiwai Hoʻolaha HoʻolahaʻOihana 1
Ka Waihona Waiwai Bond 1
Molecular Weight 195.69 g / mole
Nā Kū'ē Dissociation

 

pK = 9.98 (est)

 

ʻO kahi hōʻike maʻalahi o ka pauka Lorcaserin HCL

ʻO Lorcaserin (Belviq) kahi pīpī suppressant makemake i hoʻokumu ʻia e Arena Pharmaceuticals. Pili ia i kahi papa o nā lāʻau i kapa ʻia he agonists receptor serotonin. Hoʻonohonoho ʻia e kōkua iā ʻoe e hōʻona ma hope o kāu ʻai ʻana i ka meaʻai liʻiliʻi. Hoʻopili ia i ka makemake ma ka hoʻoulu ʻana i ka 5-HT2C nā nūnū,ʻo ia nāʻano o nā'emole serotonin i loko o kahi māhele o ka lolo (hypothalamus) e mana i ka manaʻo. Ke hōʻailona lākou i kou kino eʻoluʻolu, eʻai ihoʻoe i lalo, a laila e pau ai ke kaumaha i ka lōʻihi.

ʻO Belviq, nona ka inoa māmā (R) -8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride hemihydrate, i'ōleloʻia e lawe wahaʻia. ʻO 241.16 g / mol ka mea kaumaha kinowailua, aʻo kona kumu hoʻohālikeʻo C11H15Cl2N • 0.5H2O.ʻO kāna kumu hoʻoponopono i lalo iho nei:

 

ʻO ka lekaʻo Lorcaserin (Belviq)

 

ʻO ke solubility o Lorcaserin hydrochloride hemihydrate i ka wai i ʻoi aku ma mua o 400 mg / mL. Loaʻa i kahi papa Belviq he 10.4 milligrams o ka lorcaserin hydrochloride hemihydrate (he keʻokeʻo a keʻokeʻo keʻokeʻo keʻokeʻo), kahi like ia me 10.0 milligrams lorcaserin hydrochloride anhydrous. Loaʻa iā ia nā mea pono ʻē aʻe, e like me ka magnesium stearate NF, talc USP, FD&C Blue # 2 aluminika loko, titanium dioxide USP, polyethylene glycol NF, polyvinyl waiʻona USP, colloidal silicon dioxide NF, croscarmellose sodium NF, silicified microcrystalline cellulose a me hydroxypropyl cellulose NF.

 

ʻO ka hana o ka mana o Lorcaserin

Wahi a nā papa kuhikuhi alakaʻi o ka Food and Drug Administration (2007), hiki iā Lorcaserin ke kōkua i nā mea hōʻoia e loaʻa i ka pohō kaumaha o ka maʻi. Ke'ōleloʻia nei kēia hana kaumaha lāʻau lapaʻau i ka hana maikaʻi inā ua hui pūʻia me ka hoʻonuiʻana i kaʻoihana kino e like me kaʻai haʻahaʻa haʻahaʻa. Hiki iā ia ke kōkua nui i ka hoʻomaluʻana i ka hana kaumaha,ʻo ia me ka poʻe i kaumahaʻole (ma kahi o 27 kg / m2), aiʻole obese (BMIʻo ia ma ka liʻiliʻi o 30 kg / m2). Hiki i kēiaʻona ke kōkua i ka poʻe i hoʻokahi aʻoi aʻe paha nā hihia e pili ana i ke kaumaha, e like me ka maʻi maʻamau o 2, dyslipidemia, a iʻole ka piʻiʻana.

ʻO Lorcaserin kahi pīpī pāʻani pāʻani nui e hana like me ka 5-HT2C ke kuhi nei ka mea e loaʻa ana ma ka hypothalamus me ka kohoʻana i ka 15 mau manawa hou aku no ka 5-HT.2C  nā nūnua ma mua o 5-HT2A  a me ka hoʻonaninuiʻana i nā manawa 100 i ka kohoʻoihana kiʻekiʻe aʻe no 5-HT2C nā nūnua ma mua o ka 5-HT2B.

Aia nā mea loaʻa ʻo 5-HT2C ma kahi o ka lolo o ke kanaka a hiki ke loaʻa i ka thalamus, hypothalamus, cortex, hippocampus, choroid plexus, cerebellum, a me amygdala. ʻO ka hoʻonāukiuki ʻana o nā mea loaʻa ʻo 5-HT2C i ka hypothalamus e hoʻoulu i ka hana POMC (proopiomelanocortin) a no laila ke hāpai nei i ka hoʻoliʻiliʻi kaumaha ma o ka māʻona. Kākoʻo ʻia kēia paio e nā hoʻokolohua hoʻokolohua hōʻoia a me nā noiʻi noiʻi ʻē aʻe. ʻOiai manaʻo ʻia he kōkua nā mea loaʻa he 5-HT2C i ka hoʻoponopono ʻana i ka makemake, ka hopena endocrine, a me ke ʻano, ʻaʻole ʻike ʻia ke ʻano o ka hana i ka hoʻoponopono ʻana i ka makemake.

 

Hoʻokipa EC50 [nM] Ki[nM]
5-HT2C 39 13
5-HT2B 2380 147
5-HT2A 553 92

 

ʻO ka hoʻohanaʻana i ka paupaʻo Lorcaserin HCL

Inā mākou e noʻonoʻo pono i nā hua'ōleloʻo Lorcaserin ma laila,ʻo ia paha ka pila momona maikaʻi loa ma ka mākaʻikaʻi i kēia mau lā. ʻO kekahi o ka nui o ka nui o nā kānaka,ʻo ia hoʻi,ʻo ka poʻe i loaʻa i ke kūlana o ka lāʻau e pili ana i ke kaumaha a me nā mea momona paha e hiki ke loaʻa maikaʻi i kēia huahana.

I ka hoʻohanaʻana i ka papahana me kahi polokalamu hoʻolālā i'āponoʻia e ke kaukō, ka papahanaʻai haʻahaʻa haʻahaʻa, a me ka loli o ka nohona, hiki i ka Lorcaserin ke kōkua i kekahi e hana nui ma mua o ka loli kaumaha - hiki iā ia ke hoʻohaʻahaʻa i nā maʻi olakino e pili ana i ka nui. ka nui o ke koko, ka maʻi maʻamau, ka maʻi maʻi maʻi, a me ka make koke.

Wahi a ka Center for Disease Control,ʻo ka pauʻana o 5 wale nō i ka 10 o ka nui o ke kaumaha o ke kino e hiki ke hōʻike i kekahi mau pono olakino e like me ka hoʻoikaikaʻana i ka mea koko, ka cholesterol toto, a me ke koko.

 

 ʻO ke kumu o ka momona o Lorcaserin HCL

Pono nā mākua e lawe iʻelua mau pilina i kēlā lā i kēia lā. Ponoʻoe e lawe i nā pilina 60 i kēlā me kēia mahina. Wahi a FDA, pono i kekahi ke hoʻohana i ka lāʻau lapaʻau i ke koena o kona ola no ka mālamaʻana i ke kaumaha maikaʻi.

He mea nui e hoʻomaopopo i nā hopena maikaʻi eʻikeʻia ma hope o nā wiki 12. Ināʻaʻoleʻoe e nalowale ma kahi o 5 ka nui o kāu koʻikoʻi o ke kaumaha i kēlā manawa, ua'ōleloʻiaʻoe e haʻalele i ka hoʻohanaʻana i ka pilina. Ma muli o ka hoʻomauʻana i ka hoʻohanaʻana, hikiʻole iāʻoe ke hoʻokō a mālama i ka pohō waiwai nui.

 

ʻO Lākeleʻo HCL

He mea maikaʻi e hoʻomanaʻo i kāu ʻoihana olakino i kuhikuhi i kēia lāʻau no ka mea ua hoʻoholo lākou he ʻoi aku ka maikaʻi i loaʻa iā ʻoe ma mua o nā hopena o nā hopena ʻaoʻao. ʻO ka hapa nui o ka poʻe i lawe i kēia lāʻau ʻaʻole hōʻike i nā hopena koʻikoʻi.

Ma mua o kou lawe ʻana iā lorcaserin, e hoʻomaopopo i kāu kauka lāʻau a i ʻole kauka paha inā ʻaʻohe ʻoe i ka lāʻau. a i ʻole he maʻi ʻino ʻē aʻe kāu. Loaʻa i loko o Lorcaserin nā mea hana ʻole e hiki ai ke alakaʻi i nā hopena maʻi ʻaʻai a i ʻole nā ​​pilikia ʻē aʻe. E noi i kāu kauka lāʻau e hāʻawi iā ʻoe i nā kikoʻī.

Ma mua o ka lawe ʻana i kēia lāʻau, e hoʻomaopopo i kāu kauka lāʻau lapaʻau a i ʻole kauka e pili ana i kāu mōʻaukala olakino, e pili ana i nā pilikia o ka puʻuwai, ka maʻi diabetes, ka pilikia o ke ake, nā maʻi puʻuwai (me ka poli puʻuwai, ka maʻi puʻuwai puʻuwai, ka puʻuwai puʻuwai, ka puʻuwai ʻole) nā pilikia e hoʻonui ai i ka makaʻu o ke kūkulu ʻeha / hoʻolōʻihi ʻia i nā kāne (e like me ka penis deformed, ka maʻi o Peyronie, myeloma maha, anemia cell sickle, leukemia)

Hiki i kēia pīpī suppressant makemake ke hoʻolohi i kou noʻonoʻo a pupuʻu paha. Hiki paha i ka Marijuana a i ʻole ka waiʻona paha ke hōʻino i kēia mau hopena. Mai hoʻohana i nā mīkini, hoʻokele, a hana i kekahi mea e koi ai i ka makaʻala a hiki i kou hiki ke hana pono. E kaupalena i nā mea inu ʻona a kamaʻilio pū me kāu kauka inā hoʻohana ʻoe i ka wānana.

Inā makemake ʻoe e hana i kahi kaʻina ʻoki, pono e haʻi aku ʻoe i kāu kauka niho a kauka paha e pili ana i nā huahana āu e lawe ai (e like me nā lāʻau i hōʻike ʻole ʻia, nā huahana lāʻau, a me nā lāʻau i kuhikuhi ʻia).

Inā ʻoe e noho nei me ka maʻi diabetes, hiki i kēia pila paona kaumaha ke hoʻopili i kāu kō kō. E nānā pono i kāu pae kō kō i nā manawa maʻamau e like me ka ʻōlelo aʻoaʻo a kaʻana like i kāu mau hopena me ke kauka. E hoʻomaopopo i kāu kauka inā he haʻahaʻa kou mau hōʻailona kō kō. Pono paha kāu ʻoihana mālama ola e hoʻoponopono i kāu papahana hoʻoikaika kino, kaʻai a kauka diabetes paha.

ʻAʻole pono e lawe i kēia lāʻau i ka wā o ka hāpai keiki no ka mea e hōʻino paha ia i ka pēpē i hānau ʻole ʻia. E nīnau i kāu kauka e pili ana i ka hoʻopili ʻana i nā ʻano hilinaʻi o ka kaohi hānau. Inā hāpai ʻoe a hāpai ʻoe, e haʻi koke aku i kāu ʻoihana mālama ola.

I kēia manawa, ʻaʻole maopopo inā lilo kēia lāʻau i ka waiū umauma. I mea e pale aku ai i ka hiki i ka pēpē, ʻaʻole makemake ʻia ka hānai ʻana i ka waiū i ka hoʻohana ʻana i kēia lāʻau. E hōʻoia e nīnau aku i kāu kauka ma mua o kou hānai ʻana i ka waiū.

E heluhelu pono i ka Leaflet ʻIke Mea hoʻohana inā loaʻa mai kāu kauka ma mua o kou hoʻomaka ʻana e hoʻohana i ka lorcaserin a i kēlā me kēia manawa ke hoʻopihapiha hou ʻoe. Inā he nīnau kāu, e nīnau i kāu kauka lāʻau a i ʻole kauka.

Lawe i kēia pill suppressant makemake ma ka waha me ka ʻole o ka pāʻina e like me ke kuhikuhi a kāu kauka lāʻau, ʻelua mau manawa i kēlā me kēia lā. E hoʻohana mau i kēia lāʻau e loaʻa ai ka hapa nui. E kōkua iā ʻoe e hoʻomanaʻo, e lawe i ka pila i nā manawa like i kēlā me kēia lā.

He lāʻau maʻamauʻo Lorcaserin. Mai hoʻonui i ka uku aiʻole e lawe i kēia pila ma mua o ka mea i kauohaʻia. ʻO ke kumu i loaʻa iāʻoeʻaʻole hiki ke hoʻonui i ka wikiwiki, a hiki ke piʻi i ka hopena o nā hopena.

Hiki ke hana i nā pilikino lāʻauʻawaʻawa i ka wā e hoʻohanaʻia ai nā lāʻau lapaʻau me ka pilina lorcaserin. E haʻi i kāu kauka e pili ana i nā lāʻau a pau āu e hoʻohana ai i kēia manawa, a me nā kau'ōlelo'ē aʻe āu e hoʻomaka ai a ho'ōki paha i ka hoʻohanaʻana.

ʻAʻole iʻaeʻia ka pilikino paʻakikī paʻakikī no ka hoʻohanaʻia e nā poʻe ma lalo o 18 makahiki.

 

Pehea wau e lawe ai i ka pauka Lorcaserin HCL?

Mai hōʻoki, haʻi, aʻeha paha i kahi papa hoʻokuʻu nui. Holo wale i kahi holoʻokoʻa.

ʻO ka mea nāna e hoʻopiha i ka makemake o Lorcaserin he māhele ia o ka papahana hoʻoponopono pihaʻana, pono e komo pū me ka hoʻolālā, ka mālama kaumaha, kaʻai, a me nā mea a pau e ho'āʻo ai i kāu koko koko. E hahai pololei i kāu lāʻau lapaʻau, meaʻai pono, a me kāu hana.

E mālama i nā lāʻau i loko o ka lumi wela ma kahi o ka mahana a me ka maʻemaʻe.

E mālama i ka moʻolelo o ka nui o nā lāʻau i hoʻohanaʻia mai nā'ōmole a pau. ʻO ka pīpī paʻakikī paʻakikī he lāʻau lāʻau hōʻino ia, a ponoʻoe e noʻonoʻo inā hoʻohana kekahi i kāu lāʻau me ka palapalaʻole a iʻole kūpono paha.

Mai wehewehe i ka lorcaserin lāʻau me kekahi mea'ē aʻe. E mālama i ka lāʻau lapaʻau ma kahi i hikiʻole ai i kekahi mea'ē ke loaʻa.

 

He aha ka hana inā pilikiaʻoe i ka hua'ōlelo Lorcaserin?

E lawe wale i ka hōʻailona hemoʻole e hoʻomanaʻo kokeʻoe. Ponoʻoe e hoʻokuʻu i ka ukuʻai i hāʻuleʻole inā manawa kokoke ka manawa no ka hoʻolālā hoʻonohonoho hou. Mai lawe i kahi hōʻailona no ka hōʻailonaʻaiʻole.

 

He aha kāu e hana ai inā e loiloiʻoe iā Lorcaserin?

E nānā i ke kōkua lapaʻau kūikawā aiʻole e hoʻokae i ka laina kōkua kōkua Poison i 1-800-222-1222.

 

He aha kaʻu e hōʻalo ai i ka laweʻana i ka wā e kau ana?

Mai lawe i kekahi mea'ē aʻe ma waho o ka papahana a me nā huahana kaumahaʻole me ka'ōlelo aʻo a kāu kauka. Eia kekahi, mai hoʻohanaʻoe i nā kau anuanu aiʻole ka maʻi i ka wā e lawe ai i ka pilikino lorcaserin.

 

He aha nā lāʻau lapaʻau'ē aʻe e pā ai i ka locascasin?

Hiki i nā lāʻau aʻe ke hoʻololi i ka hana a lorcaserin:

  • ʻO kahi "triptan" ʻo ia nā migache headache lapaʻau – e like me Maxalt, Zomig almotriptan, rizatriptan, sumatriptan, frovatriptan, zolmitriptan, Imitrex, a me nā mea ʻē aʻe.
  • Cabergoline;
  • laina linezolid;
  • kekahiʻano antidepressant
  • lithium;
  • ʻO John's wort;
  • erectile hana kīnā ʻole– Levitra, Viagra avanafil, Cialis, sildenafil, tadalafil, a me nā mea ʻē aʻe;
  • alahana;
  • tryptophan (kahi i kapaʻiaʻo L-tryptophan);
  • ka hano a i ʻole ke anuanu nā lāʻau i loaʻa ka dextromethorphan; a i ʻole
  • nā lāʻau e mālama ai i ka maʻi noʻonoʻo, ke ʻano a i ʻole ka maʻi pīhoihoi.

ʻAʻole i pau ka papa inoa i luna nei. Hiki i nā lāʻau lapaʻau ke hoʻopili i ka lorcaserin, aʻaʻole nā ​​mea i hanaʻia i loko o kēia alakaʻi lāʻau.

 

Nā hōʻike a BBC e pili ana i ka palekana a me ka pono o Lorcaserin HCL (CAS 616202-92-7)

Ua nui nā hōʻike a BBC ma Lorcaserin no kaʻoihana maikaʻi akāʻo ka palekana o nā lāʻau lapaʻau. Wahi a ka BBC, he loiloi hou, i paʻiʻia ma loko o ka New England Journal of Medicine, hōʻike i ka poʻe e hoʻohana ana i ka pīpī pīpī pāʻona i ka hapa ma kahi o 8.8lb (4kg) ma kahi pūnaewele no ka liʻiliʻiʻekolu a me ka hapalua makahiki. Uaʻikeʻia nā hopena o kēia aʻoʻana he mea kānalua wale nō ka lorcaserin i kekahi o nā pila maikaʻi maikaʻi loa.

Hōʻike pū ka hōʻike i nā lāʻau lapaʻau ma muli o ka hoʻopauʻana i kaʻai, mai hoʻokomo i nā mea hoʻohana i ka hopena o ka naʻau. Ua aʻoʻia ka papahana hoʻopuka i ka poʻe kikowaena 12,000 nui a ma luna o nā māmā ma USA ma nā mahina 40.

Ma hope oʻekolu a me ka hapalua makahiki, heʻekolu manawa ka nuiʻana o nā mākua i ka lorcaserin ma mua o ka loaʻaʻole o kaʻelima a he 10% o ko lākou kino kino ma mua o ka loaʻaʻana o kahi placebo, e like me kekahi o nā mea noiʻi kaiakaʻi,ʻo Kauka'Erin Bohula.

ʻAʻole i hōʻikeʻia nā hoʻokolohua i hanaʻia ma ka naʻau o ka naʻau i nāʻano likeʻole i hoʻohālikelikeʻia me nā pahū o ka poʻe e noho ana i kahi placebo. Ma ka noʻonoʻo o kēia ka mea nui e hopohopo no ka palekana o kekahi mau hua'ōlelo pīpī liʻiliʻi, hiki i ka lorcaserin ke lilo i ka pilikino kaumaha maikaʻi loa.

ʻO ka poʻe mākua e lawe ana i ka lāʻau i ka makaʻu haʻahaʻa i ka maʻi diabetes type 2. ʻO ke kumukūʻai o ka pila ma kahi o £ 155-225 ($ 220-290) i kēlā me kēia mahina ma ka US. Hāʻawi ʻo Lorcaserin i kahi koho ʻē aʻe maikaʻi loa i nā kaʻina hana hōʻemi kaumaha e like me ke ʻoki ʻana o ka ʻōpū gastric i waena o nā poʻe ʻē aʻe.

ʻO kekahi hōʻike a BBC i hōʻike ʻia i kahi noiʻi e nā mea noiʻi ma ke Kulanui o Aberdeen's Rowett Institute nāna i alakaʻi i kahi noiʻi no ka makemake. Ua ʻōlelo nā ʻepekema ʻo kā lākou noiʻi ʻana i ka makemake i alakaʻi ai iā lākou i kekahi ʻāpana o ka lolo.

Uaʻike lākou i ka hoʻouluʻana i kēlā mau pūnaewele maʻamau me nā lāʻau i hiki iā lākou ke hoʻohaʻahaʻa i kaʻai. Ma muli o ka hanaʻana a ka mō'ī i kēia hana,ʻaʻole i weheʻia nā hopena o kēia aʻoʻana i nā puka no nā lāʻau hou e like me ka lorcaserin akā ua hoʻoikaika pū i ka mea iʻikeʻia e nā poʻe akamai e pili ana i ka lorcaserin-kona palekana a me ka maikaʻi.

 


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