ʻO kaʻepa momona o Lencaserin HCL

ʻO Lorcaserin hydrochloride Powder Video-AASraw

ʻO Raw Lorcaserin hydrochloride Powder Nā mea maʻamau

Heaha is Lorcaserin hydrochloride Powder?

ʻO Lorcaserin hydrochloride he hydrochloride i loaʻa ma ka hopena o ka lorcaserin me hoʻokahi like o ka waika hydrochloric. Hoʻohana ʻia ma ke ʻano he lāʻau anti-obesity. He kuleana ko ia ma ke ʻano he serotonergic agonist a me kahi mea hoʻohaʻahaʻa makemake.

Hoʻopili ʻo Lorcaserin hydrochloride i nā hōʻailona kemika i ka lolo e hoʻomalu i ka ʻai. ʻO Lorcaserin HCL hana ka pauda ma ke kōkua ʻana iā ʻoe e piha me nā meaʻai liʻiliʻi. Hoʻohana ʻia ka pauka Lorcaserin hydrochloride me ka meaʻai a me ka hoʻomaʻamaʻa e mālama i ka momona. Hoʻohana ʻia ʻo Lorcaserin hydrochloride pauka i kekahi manawa e mālama i ka momona e pili ana i ka maʻi diabetes, cholesterol kiʻekiʻe, a i ʻole ke koko kiʻekiʻe.

He aha ka maikaʻi o Lorcaserin hydrochloride?

Hoʻohana ʻia ʻo Lorcaserin hydrochloride e kōkua i ka poʻe makua i ka momona a i ʻole ke kaumaha a loaʻa nā pilikia olakino pili i ke kaumaha e lilo i ke kaumaha a mālama i ka loaʻa ʻana o kēlā kaumaha. Pono e hoʻohana ʻia ʻo Lorcaserin me kahi meaʻai hoʻemi-calorie a me kahi hoʻolālā hoʻolālā. Aia ʻo Lorcaserin i kahi papa o nā lāʻau i kapa ʻia ʻo serotonin receptor agonists. Hoʻohana ia ma ka hoʻonui ʻana i ka manaʻo o ka māʻona i mea e emi ai ka ʻai ʻana.

Hoʻohana pū ʻia ʻo Lorcaserin hydrochloride me kahi meaʻai hoʻemi-calorie a me ka hoʻomaʻamaʻa kūpono e kōkua iā ʻoe e lilo i ke kaumaha. Hoʻohana ʻia ia i ka poʻe paona nui i loaʻa i ka maʻi diabetes, ke koko kiʻekiʻe, ka cholesterol kiʻekiʻe, a i ʻole ka maʻi puʻuwai.

ʻO ka bnā pono o Lorcaserin hydrochloride

ʻO Lorcaserin hydrochloride kahi lāʻau lapaʻau i hāʻawi ʻia e hoʻoikaika i ka pohō kaumaha. Hoʻohana ʻia ia me ka meaʻai a me ka hoʻoikaika kino i nā poʻe pākeke keu me kahi pilikia olakino pili i ke kaumaha a i ʻole nā ​​​​mākua momona e lilo i ke kaumaha a mālama ʻia.

ʻO Lorcaserin hydrochloride kahi agonist receptor serotonin 2C (5-HT2C). Ua manaʻo ʻia ʻo lorcaserin e hoʻoulu i nā mea hoʻokipa 5-HT2C i ka hypothalamus, kahi o ka lolo i ʻike ʻia. pāʻani i kahi kuleana nui i ka hooponopono ana i ka pololi a me ka ai ana. Ma ka hoʻouluʻana i kēia mau mea loaʻa, hiki i ka lorcaserin ke hoʻemi i kaʻaiʻana ma ka ho'ēmiʻana i ka makemake a me ka hoʻonaneaʻana o ke kanaka ma hope o kaʻaiʻana i ka meaʻai ma mua o ka mea maʻamau.

ʻO Lorcaserin hydrochloride he serotonin 2C receptor agonist i hōʻikeʻia no ka mālamaʻana i ka mālamaʻana i ke kaumaha mau i nā mākua me ka helu helu kino (BMI) o 30 aʻoi aku paha (obese) ma keʻano he hoʻohui i kaʻai a me ka hoʻoikaika kino. Ua'āponoʻia hoʻi ka lorcaserin no ka hoʻohanaʻana e nā poʻe mākua me ka BMI o 27 aʻoi aku paha (ke kaumaha) a loaʻa iā lākou ma kahi o hoʻokahi maʻi e pili ana i ke kaumaha e like me ke koko kiʻekiʻe (hypertension), type 2 diabetes, aiʻole ka cholesterol kiʻekiʻe (dyslipidemia).

Lorcaserin hydrochloride hoʻohana ʻia ma ke ʻano he lāʻau anti-obesity

ʻO ka momona ka mea nui o ke olakino e pono ai i nā hoʻolālā palekana a maikaʻi hoʻi e hoʻoponopono ai i ka maʻi maʻi momona. ʻO Lorcaserin he agonist serotonergic kiko'ī i ka 5HT-2C receptor i'āponoʻia no ka mālama mauʻana o ka momona i nā maʻi me ka BMI ≥ 30 kg / m (2) a iʻole ka BMI ≥ 27 kg / m (2) me nā mea pili i ka momona.

ʻO Lorcaserin kahi agonist serotonergic koho nui loa i hoʻolālā ʻia e hoʻēmi i nā pilikia e pili ana i nā mea hana mua i kēia papa. Ma nā lāʻau lapaʻau, ua ʻae maikaʻi ʻia a hoʻohua mai i kahi haʻahaʻa akā kūpono i ke kino kaumaha lilo me ka hoʻomaikaʻi nui ʻana i nā ʻāpana cardiometabolic. Pono e loiloi ʻia ka maikaʻi o ka lāʻau lapaʻau ma nā pule he 12 (≥ 5% ka pohō kaumaha) e ʻike ai i ka poʻe pane. loaʻa i ka pohō kaumaha loa a me ka pōmaikaʻi metabolic mai ka lāʻau lapaʻau lōʻihi. ʻO nā hopena o ka hopena o ka hopena cardiovascular (CAMELLIA TIMI 61) e hoʻoholo i ke kuleana o ka lorcaserin i ka pale mua ʻana i ka maʻi maʻi i nā poʻe momona / momona a me kona hoʻohana ʻana i ka heluna kiʻekiʻe o ka poʻe maʻi me ka maʻi maʻi cardiovascular a i ʻole nā ​​kumu pilikia cardiovascular. .

Kahi e kūʻai Lorcaserin hydrochloride Pauda?

Hoʻohana ʻia ʻo Lorcaserin e kōkua i ka poʻe ʻōpio i ka momona a i ʻole ke kaumaha a loaʻa nā pilikia olakino pili i ke kaumaha e lilo i ke kaumaha a mālama i ka loaʻa ʻana o kēlā kaumaha. Pono e hoʻohana ʻia ʻo Lorcaserin me kahi meaʻai hoʻemi-calorie a me kahi hoʻolālā hoʻolālā. Aia ʻo Lorcaserin i kahi papa o nā lāʻau i kapa ʻia ʻo serotonin receptor agonists. Hoʻohana ia ma ka hoʻonui ʻana i ka manaʻo o ka māʻona i mea e emi ai ka ʻai ʻana.

ʻO Raw Lorcaserin hydrochloride Powder Testing Report-HNMR

He aha ka HNMR a he aha ka HNMR spectrum e haʻi iā ʻoe? ʻO H Nuclear Magnetic Resonance (INMR) spectroscopy kahi ʻenehana kemika analytical i hoʻohana ʻia i ka hoʻokele maikaʻi a me ka noiʻi no ka hoʻoholo ʻana i ka ʻike a me ka maʻemaʻe o kahi laʻana a me kona ʻano molekala. No ka laʻana, hiki i ka NMR ke hoʻokaʻawale i nā hui pū ʻia i ʻike ʻia. No nā pūhui i ʻike ʻole ʻia, hiki ke hoʻohana ʻia ka NMR (a i ʻole e hoʻohālikelike ʻia i nā hale waihona puke spectral a i ʻole e hoʻokaʻawale pololei i ke ʻano kumu. e like me ka hoʻololi conformational, hoʻololi i ka pae, solubility, a me ka diffusion.

Lorcaserin hydrochloride(1431697-94-7)-COA

Lorcaserin hydrochloride(1431697-94-7)-COA

Pehea e kūʻai Lorcaserin hydrochloride Pauka mai AASraw?

❶I Hoʻokaʻaʻike iā mākou ma kā mākou ʻōnaehana nīnau leka uila, a i ʻole e waiho i kāu helu WhatsApp iā mākou, e hoʻopili aku kā mākou mea kūʻai aku (CSR) iā ʻoe i nā hola 12.

❷E hāʻawi iā mākou i kāu helu a me kāu helu wahi i nīnau ʻia.

❸Na kā mākou CSR e hāʻawi iā ʻoe i ka ʻōlelo ʻōlelo, ka manawa uku, ka helu ʻimi, nā ala lawe, a me ka lā i manaʻo ʻia e hiki mai ai (ETA).

❹E uku ʻia a hoʻouna ʻia nā waiwai i loko o 12 mau hola.

❺ Loaʻa nā waiwai a hāʻawi i nā manaʻo.

Mea kākau o kēia ʻatikala:
Kauka Monique Ua puka 'o Hong mai ke Kula Nui o UK Imperial College London Faculty of Medicine

Mea kākau moʻolelo puke moʻolelo ʻepekema:
1. Stefan Wagner
ʻO ka Rowett Institute, University of Aberdeen, Aberdeen, UK
Ua hāʻawi like ʻo Stefan Wagner lāua ʻo Daniel I. Brierley i kēia hana.
2. Qihua Zhu
Jiangsu Key Laboratory of Hoʻolālā a me ka hoʻolālā lāʻau lapaʻau
Keʻena ʻOihana Kemika Lapaʻau, Ke Kulanui ʻOihana Lapaʻau Kina, Nanjing, 210009, Kina
3. Thiago F. Ribeiro
Instituto de Química, Universidade Federal de Goiás, Campus Samambaia, PO Box 131, Goiânia, GO 74690-900, Palakila
4. Dattatraya V. Wani
Ke Keʻena ʻOihana Lapaʻau Lapaʻau, Maulana Azad Education Trust's YB Chavan College of Pharmacy, Aurangabad, Maharashtra, India
ʻAʻole ʻae kēia kauka/ʻepekema i ke kūʻai, kūʻai ʻana, a hoʻohana paha i kēia huahana no kekahi kumu. ʻAʻohe pili a pili ʻole ʻo Aasraw, i hōʻike ʻia a i ʻole, me kēia kauka. ʻO ke kumu o ka haʻi ʻana i kēia kauka, ʻo ia ka hoʻomaikaʻi ʻana a me ka hoʻomaikaʻi ʻana i ka hana noiʻi a me ka hoʻomohala piha i hana ʻia e nā ʻepekema e hana nei i kēia mea.

Reference

[1] Belviq (lorcaserin hydrochloride) papa [Eisai, Inc]”. DailyMed. Eisai, Inc. ʻAukake 2012. Waiho ʻia mai ka mea kumu ma 21 ʻOkakopa 2013. Kiʻi ʻia i ka lā 21 ʻOkakopa 2013.

[2] "Ke noi nei ʻo FDA i ka haʻalele ʻana i ka lāʻau kaumaha kaumaha Belviq, Belviq XR (lorcaserin) mai ka mākeke". US Food and Drug Administration (FDA). 14 Ianuali 2020. Kiʻi ʻia 1 ʻApelila 2020.

[3] "FDA Ma ka pōkole: Noi ʻo FDA e hoʻihoʻi manawaleʻa i ka lāʻau hoʻemi kaumaha ma hope o ka hōʻike ʻana o ka hoʻāʻo ʻana i kahi maʻi maʻi maʻi maʻi". FDA. 13 Pepeluali 2020.

[4] "Belviq XR (lorcaserin hydrochloride) papa hoʻokuʻu lōʻihi". US Food and Drug Administration (FDA). 26 ʻOkakopa 2016. Kiʻi ʻia 14 Ianuali 2020.

[5] "Papa Hoʻopiʻi Lapaʻau: Belviq (lorcaserin hydrochloride) Papa NDA #022529". US Food and Drug Administration (FDA). 7 ʻAukake 2012. Kiʻi ʻia ma 14 Ianuali 2020.

E kiʻi i kahi hōʻaiʻē nui