Product Description
ʻO Lorcaserin hydrochloride Powder Video-AASraw
ʻO Raw Lorcaserin hydrochloride Powder Nā mea maʻamau
| Name: | ʻO Lorcaserin ka lepo |
| CAS: | 1431697-94-7 |
| Kaulike Molecular: | C11H15Cl2N |
| Kaumaha Molecular: | 232.1525 |
| Wahi Manaʻo: | 212 ° C |
| Hōʻoia Kōkua: | -20 ℃ |
| kala like 'ole: | ʻO ka pauma |
Heaha is Lorcaserin hydrochloride Powder?
ʻO Lorcaserin hydrochloride kahi hydrochloride i loaʻa ma ka hopena o ka lorcaserin me hoʻokahi like o ka waika hydrochloric. Hoʻohana ʻia ma ke ʻano he lāʻau anti-obesity. He kuleana ko ia ma ke ʻano he serotonergic agonist a me kahi mea hoʻohaʻahaʻa makemake.
Hoʻopili ʻo Lorcaserin hydrochloride i nā hōʻailona kemika i ka lolo e hoʻomalu i ka ʻai. Hana ʻia ʻo Lorcaserin HCL pauka ma ke kōkua ʻana iā ʻoe e piha me nā mea liʻiliʻi liʻiliʻi. Hoʻohana ʻia ʻo Lorcaserin hydrochloride pauka me ka meaʻai a me ka hoʻomaʻamaʻa e mālama ai i ka momona. .
He aha ka maikaʻi o Lorcaserin hydrochloride?
Hoʻohana ʻia ʻo Lorcaserin hydrochloride e kōkua i ka poʻe makua i ka momona a i ʻole ke kaumaha a loaʻa nā pilikia olakino pili i ke kaumaha e lilo i ke kaumaha a mālama i ka loaʻa ʻana o kēlā kaumaha. Pono e hoʻohana ʻia ʻo Lorcaserin me kahi meaʻai calorie hoʻemi a me kahi hoʻolālā hoʻolālā. Aia ʻo Lorcaserin i kahi papa o nā lāʻau i kapa ʻia ʻo serotonin receptor agonists. Hoʻohana ia ma ka hoʻonui ʻana i ka manaʻo o ka māʻona i mea e emi ai ka ʻai ʻana.
Hoʻohana pū ʻia ʻo Lorcaserin hydrochloride me kahi meaʻai hoʻemi-calorie a me ka hoʻomaʻamaʻa kūpono e kōkua iā ʻoe e lilo i ke kaumaha. Hoʻohana ʻia ia i ka poʻe paona nui i loaʻa i ka maʻi diabetes, ke koko kiʻekiʻe, ka cholesterol kiʻekiʻe, a i ʻole ka maʻi puʻuwai.
ka Nā pōmaikaʻi o Lorcaserin hydrochloride
ʻO Lorcaserin hydrochloride kahi lāʻau lapaʻau i hāʻawi ʻia e hoʻoikaika i ka pohō kaumaha. Hoʻohana ʻia ia me ka meaʻai a me ka hoʻoikaika kino i nā poʻe pākeke keu me kahi pilikia olakino pili i ke kaumaha a i ʻole nā mākua momona e lilo i ke kaumaha a mālama ʻia.
ʻO Lorcaserin hydrochloride kahi agonist receptor serotonin 2C (5-HT2C). Ua manaʻoʻia ka lorcaserin e hoʻoulu i nā mea hoʻokipa 5-HT2C i ka hypothalamus, kahi o ka lolo iʻikeʻia e hana nui i ka hoʻoponoponoʻana i ka pōloli a me kaʻai. Ma ka ho'ālaʻana i kēia mau mea loaʻa, hiki i ka lorcaserin ke ho'ēmi i kaʻaiʻai ma ka ho'ēmiʻana i kaʻai a me ka hoʻouluʻana i ke kanaka ma hope o kaʻaiʻana i ka meaʻai liʻiliʻi ma mua o ka mea maʻamau.
ʻO Lorcaserin hydrochloride he serotonin 2C receptor agonist i hōʻikeʻia no ka mālamaʻana i ka mālamaʻana i ke kaumaha mau i nā mākua me ka helu helu kino (BMI) o 30 aʻoi aku paha (obese) ma keʻano he hoʻohui i kaʻai a me ka hoʻoikaika kino. Ua'āponoʻia hoʻi ka lorcaserin no ka hoʻohanaʻana e nā poʻe mākua me ka BMI o 27 aʻoi aku paha (ke kaumaha) a loaʻa iā lākou ma kahi o hoʻokahi maʻi e pili ana i ke kaumaha e like me ke koko kiʻekiʻe (hypertension), type 2 diabetes, aiʻole ka cholesterol kiʻekiʻe (dyslipidemia).
Lorcaserin hydrochloride hoʻohana ʻia ma ke ʻano he lāʻau anti-obesity
ʻO ka momona ka mea nui o ke olakino e pono ai i nā hoʻolālā palekana a maikaʻi hoʻi e hoʻoponopono ai i ka maʻi maʻi momona. ʻO Lorcaserin he agonist serotonergic kiko'ī i ka 5HT-2C receptor i'āponoʻia no ka mālama mauʻana o ka momona i nā maʻi me ka BMI ≥ 30 kg / m (2) a iʻole ka BMI ≥ 27 kg / m (2) me nā mea pili i ka momona.
ʻO Lorcaserin kahi agonist serotonergic koho nui loa i hoʻolālā ʻia e hoʻēmi i nā pilikia e pili ana i nā mea hana mua i kēia papa. I ka therapeutic doses, ua ʻae maikaʻi ʻia a hoʻohua i ke kaumaha haʻahaʻa akā kūpono i ke kino me ka hoʻomaikaʻi nui ʻana i nā ʻāpana cardiometabolic. Pono e loiloi ʻia ka maikaʻi o ka lāʻau lapaʻau ma nā pule he 12 (≥ 5% pohō kaumaha) e ʻike ai i nā mea pane e loaʻa i ka pohō kaumaha a me ka pōmaikaʻi metabolic mai ka lāʻau lōʻihi. ʻO nā hopena o ka hopena o ka hopena cardiovascular (CAMELLIA TIMI 61) e hoʻoholo i ke kuleana o ka lorcaserin i ka pale mua ʻana i ka maʻi maʻi i nā poʻe keu / momona a me kona hoʻohana ʻana i ka heluna kiʻekiʻe o nā maʻi me ka maʻi maʻi cardiovascular a i ʻole nā kumu pilikia cardiovascular.
Kahi e kūʻai Lorcaserin hydrochloride Pauda?
Hoʻohana ʻia ʻo Lorcaserin e kōkua i ka poʻe ʻōpio i ka momona a i ʻole ke kaumaha a loaʻa nā pilikia olakino pili i ke kaumaha e lilo i ke kaumaha a mālama i ka loaʻa ʻana o kēlā kaumaha. Pono e hoʻohana ʻia ʻo Lorcaserin me kahi meaʻai calorie hoʻemi a me kahi hoʻolālā hoʻolālā. Aia ʻo Lorcaserin i kahi papa o nā lāʻau i kapa ʻia ʻo serotonin receptor agonists. Hoʻohana ia ma ka hoʻonui ʻana i ka manaʻo o ka māʻona i mea e emi ai ka ʻai ʻana.
ʻO Raw Lorcaserin hydrochloride Powder Testing Report-HNMR
He aha ka HNMR a He aha ka HNMR spectrum e haʻi aku iā ʻoe? ʻO H Nuclear Magnetic Resonance (NMR) spectroscopy kahi ʻenehana kemika analytical i hoʻohana ʻia i ka hoʻokele maikaʻi a me ka noiʻi no ka hoʻoholo ʻana i ka ʻike a me ka maʻemaʻe o kahi laʻana a me kona ʻano molekala. No ka laʻana, hiki i ka NMR ke hoʻokaʻawale i nā hui pū ʻia i ʻike ʻia. No nā pūhui i ʻike ʻole ʻia, hiki ke hoʻohana ʻia ka NMR e hoʻohālikelike i nā hale waihona puke spectral a i ʻole e kuhi pololei i ke ʻano kumu. Ke ʻike ʻia ke ʻano kumu, hiki ke hoʻohana ʻia ka NMR no ka hoʻoholo ʻana i ka conformation molecular i ka hopena a me ke aʻo ʻana i nā waiwai kino ma ka pae molekala e like me ka hoʻololi conformational, nā hoʻololi ʻana, ka solubility, a me ka diffusion.
Lorcaserin hydrochloride(1431697-94-7)-COA
Lorcaserin hydrochloride(1431697-94-7)-COA
Pehea e kūʻai Lorcaserin hydrochloride Pauka mai AASraw?
❶E hoʻokaʻaʻike mai iā mākou ma kā mākou ʻōnaehana nīnau leka uila, a i ʻole e waiho i kāu helu whatsapp iā mākou, e hoʻopili kā mākou mea kūʻai aku (CSR) me ʻoe i loko o 12 mau hola.
❷E hāʻawi mai iā mākou i kāu helu a me kāu helu wahi i nīnau ʻia.
❸Na kā mākou CSR e hāʻawi iā ʻoe i ka ʻōlelo, ka manawa uku, ka helu ʻimi, nā ala hoʻouna a me ka lā i manaʻo ʻia (ETA).
❹E uku ʻia a hoʻouna ʻia nā waiwai i loko o 12 mau hola.
❺ Loaʻa nā waiwai a hāʻawi i nā manaʻo.
Mea kākau o kēia ʻatikala:
Kauka Monique Ua puka 'o Hong mai ke Kula Nui o UK Imperial College London Faculty of Medicine
Mea kākau moʻolelo puke moʻolelo ʻepekema:
1. Stefan Wagner
ʻO ka Rowett Institute, University of Aberdeen, Aberdeen, UK
Ua hāʻawi like ʻo Stefan Wagner lāua ʻo Daniel I. Brierley i kēia hana.
2. Qihua Zhu
Jiangsu Key Laboratory of Drug Design and Optimization
Keʻena ʻOihana Kemika Lapaʻau, Ke Kulanui ʻOihana Lapaʻau Kina, Nanjing, 210009, Kina
3. Thiago F. Ribeiro
Instituto de Química, Universidade Federal de Goiás, Campus Samambaia, PO Box 131, Goiânia, GO 74690-900, Palakila
4. Dattatraya V. Wani
Ke Keʻena ʻOihana Lapaʻau Lapaʻau, Maulana Azad Education Trust's YB Chavan College of Pharmacy, Aurangabad, Maharashtra, India
ʻAʻole ʻae kēia kauka/ ʻepekema i ke kūʻai, kūʻai ʻana, a hoʻohana paha i kēia huahana no kekahi kumu. ʻAʻohe pili a pili ʻole ʻo Aasraw, i hōʻike ʻia a i ʻole, me kēia kauka. ʻO ke kumu o ka haʻi ʻana i kēia kauka, ʻo ia ka hoʻomaikaʻi, hoʻomaikaʻi a hoʻomaikaʻi i ka hana noiʻi a me ka hoʻomohala piha i hana ʻia e nā ʻepekema e hana nei i kēia mea.
Reference
[1] Belviq (lorcaserin hydrochloride) papa [Eisai, Inc]”. DailyMed. Eisai, Inc. ʻAukake 2012. Waiho ʻia mai ka mea kumu ma 21 ʻOkakopa 2013. Kiʻi ʻia i ka lā 21 ʻOkakopa 2013.
[2] "Ke noi nei ʻo FDA i ka haʻalele ʻana i ka lāʻau kaumaha kaumaha Belviq, Belviq XR (lorcaserin) mai ka mākeke". US Food and Drug Administration (FDA). 14 Ianuali 2020. Kiʻi ʻia 1 ʻApelila 2020.
[3] "FDA Ma ka pōkole: Noi ʻo FDA e hoʻihoʻi manawaleʻa i ka lāʻau hoʻemi kaumaha ma hope o ka hōʻike ʻana o ka hoʻāʻo ʻana i kahi maʻi maʻi maʻi maʻi". FDA. 13 Pepeluali 2020.
[4] "Belviq XR (lorcaserin hydrochloride) papa hoʻokuʻu lōʻihi". US Food and Drug Administration (FDA). 26 ʻOkakopa 2016. Kiʻi ʻia 14 Ianuali 2020.
[5] "Papa Hoʻopiʻi Lapaʻau: Belviq (lorcaserin hydrochloride) Papa NDA #022529". US Food and Drug Administration (FDA). 7 ʻAukake 2012. Kiʻi ʻia ma 14 Ianuali 2020.
